![[Experimental]](figures/lifecycle-experimental.svg)
Usage
component(
object,
name = c("cov_type", "n_theta", "n_subjects", "n_timepoints", "n_obs", "beta_vcov",
"beta_vcov_complete", "varcor", "formula", "dataset", "n_groups", "reml",
"convergence", "evaluations", "method", "conv_message", "call", "theta_est",
"beta_est", "beta_est_complete", "beta_aliased", "x_matrix", "y_vector",
"neg_log_lik", "jac_list", "theta_vcov")
)Details
Available component() names are as follows:
call: low-level function call which generated the model.formula: model formula.dataset: data set name.cov_type: covariance structure type.n_theta: number of parameters.n_subjects: number of subjects.n_timepoints: number of modeled time points.n_obs: total number of observations.reml: was REML used (ML was used ifFALSE).neg_log_lik: negative log likelihood.convergence: convergence code from optimizer.conv_message: message accompanying the convergence code.evaluations: number of function evaluations for optimization.method: Adjustment method which was used (formmrmobjects), otherwiseNULL(formmrm_tmbobjects).beta_vcov: estimated variance-covariance matrix of coefficients (excluding aliased coefficients). For Kenward-Roger methods, the adjusted covariance matrix is returned (to still obtain the unadjusted covariance matrix useobject$beta_vcov).beta_vcov_complete: estimated variance-covariance matrix including aliased coefficients with entries set toNA.varcor: estimated covariance matrix for residuals. If there are multiple groups, a named list of estimated covariance matrices for residuals will be returned. The names are the group levels.theta_est: estimated variance parameters.beta_est: estimated coefficients (excluding aliased coefficients).beta_est_complete: estimated coefficients including aliased coefficients set toNA.beta_aliased: whether each coefficient was aliased (i.e. cannot be estimated) or not.theta_vcov: estimated variance-covariance matrix of variance parameters.x_matrix: design matrix used (excluding aliased columns).y_vector: response vector used.jac_list: Jacobian, seeh_jac_list()for details.
Examples
fit <- mmrm(
formula = FEV1 ~ RACE + SEX + ARMCD * AVISIT + us(AVISIT | USUBJID),
data = fev_data
)
# Get all available components.
component(fit)
#> $cov_type
#> [1] "us"
#>
#> $n_theta
#> [1] 10
#>
#> $n_subjects
#> [1] 197
#>
#> $n_timepoints
#> [1] 4
#>
#> $n_obs
#> [1] 537
#>
#> $beta_vcov
#> (Intercept) RACEBlack or African American
#> (Intercept) 0.7859971 -0.226212328
#> RACEBlack or African American -0.2262123 0.389969478
#> RACEWhite -0.1771113 0.181466304
#> SEXFemale -0.1684152 0.031537926
#> ARMCDTRT -0.5674809 0.028374129
#> AVISITVIS2 -0.4227565 0.002972514
#> AVISITVIS3 -0.5231223 0.010825469
#> AVISITVIS4 -0.4406442 0.002205681
#> ARMCDTRT:AVISITVIS2 0.4225282 0.005382569
#> ARMCDTRT:AVISITVIS3 0.5218971 0.011420575
#> ARMCDTRT:AVISITVIS4 0.4489247 -0.012589283
#> RACEWhite SEXFemale ARMCDTRT
#> (Intercept) -0.177111308 -0.168415217 -0.567480906
#> RACEBlack or African American 0.181466304 0.031537926 0.028374129
#> RACEWhite 0.443035801 0.023364777 -0.042968995
#> SEXFemale 0.023364777 0.282971189 0.001814594
#> ARMCDTRT -0.042968995 0.001814594 1.153791725
#> AVISITVIS2 -0.003149280 0.006471853 0.419528600
#> AVISITVIS3 -0.002952986 0.006771404 0.517277529
#> AVISITVIS4 -0.008230720 0.004088901 0.440653554
#> ARMCDTRT:AVISITVIS2 0.013485683 -0.016801299 -0.845758354
#> ARMCDTRT:AVISITVIS3 0.006720617 -0.024696304 -1.044355829
#> ARMCDTRT:AVISITVIS4 0.002967665 -0.009038640 -0.877606881
#> AVISITVIS2 AVISITVIS3 AVISITVIS4
#> (Intercept) -0.422756455 -0.523122299 -0.440644229
#> RACEBlack or African American 0.002972514 0.010825469 0.002205681
#> RACEWhite -0.003149280 -0.002952986 -0.008230720
#> SEXFemale 0.006471853 0.006771404 0.004088901
#> ARMCDTRT 0.419528600 0.517277529 0.440653554
#> AVISITVIS2 0.642749706 0.399048940 0.368340113
#> AVISITVIS3 0.399048940 0.676823960 0.401800094
#> AVISITVIS4 0.368340113 0.401800094 1.723478787
#> ARMCDTRT:AVISITVIS2 -0.643020114 -0.399203255 -0.368624024
#> ARMCDTRT:AVISITVIS3 -0.399238901 -0.676484876 -0.401792995
#> ARMCDTRT:AVISITVIS4 -0.368506585 -0.402167824 -1.723586879
#> ARMCDTRT:AVISITVIS2 ARMCDTRT:AVISITVIS3
#> (Intercept) 0.422528163 0.521897062
#> RACEBlack or African American 0.005382569 0.011420575
#> RACEWhite 0.013485683 0.006720617
#> SEXFemale -0.016801299 -0.024696304
#> ARMCDTRT -0.845758354 -1.044355829
#> AVISITVIS2 -0.643020114 -0.399238901
#> AVISITVIS3 -0.399203255 -0.676484876
#> AVISITVIS4 -0.368624024 -0.401792995
#> ARMCDTRT:AVISITVIS2 1.275359305 0.805849821
#> ARMCDTRT:AVISITVIS3 0.805849821 1.410501907
#> ARMCDTRT:AVISITVIS4 0.728711516 0.796418986
#> ARMCDTRT:AVISITVIS4
#> (Intercept) 0.448924745
#> RACEBlack or African American -0.012589283
#> RACEWhite 0.002967665
#> SEXFemale -0.009038640
#> ARMCDTRT -0.877606881
#> AVISITVIS2 -0.368506585
#> AVISITVIS3 -0.402167824
#> AVISITVIS4 -1.723586879
#> ARMCDTRT:AVISITVIS2 0.728711516
#> ARMCDTRT:AVISITVIS3 0.796418986
#> ARMCDTRT:AVISITVIS4 3.425654435
#>
#> $beta_vcov_complete
#> (Intercept) RACEBlack or African American
#> (Intercept) 0.7859971 -0.226212328
#> RACEBlack or African American -0.2262123 0.389969478
#> RACEWhite -0.1771113 0.181466304
#> SEXFemale -0.1684152 0.031537926
#> ARMCDTRT -0.5674809 0.028374129
#> AVISITVIS2 -0.4227565 0.002972514
#> AVISITVIS3 -0.5231223 0.010825469
#> AVISITVIS4 -0.4406442 0.002205681
#> ARMCDTRT:AVISITVIS2 0.4225282 0.005382569
#> ARMCDTRT:AVISITVIS3 0.5218971 0.011420575
#> ARMCDTRT:AVISITVIS4 0.4489247 -0.012589283
#> RACEWhite SEXFemale ARMCDTRT
#> (Intercept) -0.177111308 -0.168415217 -0.567480906
#> RACEBlack or African American 0.181466304 0.031537926 0.028374129
#> RACEWhite 0.443035801 0.023364777 -0.042968995
#> SEXFemale 0.023364777 0.282971189 0.001814594
#> ARMCDTRT -0.042968995 0.001814594 1.153791725
#> AVISITVIS2 -0.003149280 0.006471853 0.419528600
#> AVISITVIS3 -0.002952986 0.006771404 0.517277529
#> AVISITVIS4 -0.008230720 0.004088901 0.440653554
#> ARMCDTRT:AVISITVIS2 0.013485683 -0.016801299 -0.845758354
#> ARMCDTRT:AVISITVIS3 0.006720617 -0.024696304 -1.044355829
#> ARMCDTRT:AVISITVIS4 0.002967665 -0.009038640 -0.877606881
#> AVISITVIS2 AVISITVIS3 AVISITVIS4
#> (Intercept) -0.422756455 -0.523122299 -0.440644229
#> RACEBlack or African American 0.002972514 0.010825469 0.002205681
#> RACEWhite -0.003149280 -0.002952986 -0.008230720
#> SEXFemale 0.006471853 0.006771404 0.004088901
#> ARMCDTRT 0.419528600 0.517277529 0.440653554
#> AVISITVIS2 0.642749706 0.399048940 0.368340113
#> AVISITVIS3 0.399048940 0.676823960 0.401800094
#> AVISITVIS4 0.368340113 0.401800094 1.723478787
#> ARMCDTRT:AVISITVIS2 -0.643020114 -0.399203255 -0.368624024
#> ARMCDTRT:AVISITVIS3 -0.399238901 -0.676484876 -0.401792995
#> ARMCDTRT:AVISITVIS4 -0.368506585 -0.402167824 -1.723586879
#> ARMCDTRT:AVISITVIS2 ARMCDTRT:AVISITVIS3
#> (Intercept) 0.422528163 0.521897062
#> RACEBlack or African American 0.005382569 0.011420575
#> RACEWhite 0.013485683 0.006720617
#> SEXFemale -0.016801299 -0.024696304
#> ARMCDTRT -0.845758354 -1.044355829
#> AVISITVIS2 -0.643020114 -0.399238901
#> AVISITVIS3 -0.399203255 -0.676484876
#> AVISITVIS4 -0.368624024 -0.401792995
#> ARMCDTRT:AVISITVIS2 1.275359305 0.805849821
#> ARMCDTRT:AVISITVIS3 0.805849821 1.410501907
#> ARMCDTRT:AVISITVIS4 0.728711516 0.796418986
#> ARMCDTRT:AVISITVIS4
#> (Intercept) 0.448924745
#> RACEBlack or African American -0.012589283
#> RACEWhite 0.002967665
#> SEXFemale -0.009038640
#> ARMCDTRT -0.877606881
#> AVISITVIS2 -0.368506585
#> AVISITVIS3 -0.402167824
#> AVISITVIS4 -1.723586879
#> ARMCDTRT:AVISITVIS2 0.728711516
#> ARMCDTRT:AVISITVIS3 0.796418986
#> ARMCDTRT:AVISITVIS4 3.425654435
#>
#> $varcor
#> VIS1 VIS2 VIS3 VIS4
#> VIS1 40.553664 14.396045 4.9747288 13.3866534
#> VIS2 14.396045 26.571483 2.7854661 7.4744790
#> VIS3 4.974729 2.785466 14.8978517 0.9082111
#> VIS4 13.386653 7.474479 0.9082111 95.5568420
#>
#> $formula
#> [1] "FEV1 ~ RACE + SEX + ARMCD * AVISIT + us(AVISIT | USUBJID)"
#>
#> $dataset
#> [1] "fev_data"
#>
#> $n_groups
#> [1] 1
#>
#> $reml
#> [1] TRUE
#>
#> $convergence
#> [1] 0
#>
#> $evaluations
#> function gradient
#> 15 15
#>
#> $method
#> [1] "Satterthwaite"
#>
#> $conv_message
#> [1] "CONVERGENCE: REL_REDUCTION_OF_F <= FACTR*EPSMCH"
#>
#> $call
#> fit_mmrm(formula = FEV1 ~ RACE + SEX + ARMCD * AVISIT + us(AVISIT |
#> USUBJID), data = "fev_data", weights = weights, reml = reml,
#> control = control)
#>
#> $theta_est
#> [1] 1.85131306 1.53312022 1.32799829 2.25400062 0.48798054 0.20701987
#> [7] 0.05832020 0.22067693 0.06169127 -0.02401589
#>
#> $beta_est
#> (Intercept) RACEBlack or African American
#> 30.77747548 1.53049977
#> RACEWhite SEXFemale
#> 5.64356535 0.32606192
#> ARMCDTRT AVISITVIS2
#> 3.77423004 4.83958845
#> AVISITVIS3 AVISITVIS4
#> 10.34211288 15.05389826
#> ARMCDTRT:AVISITVIS2 ARMCDTRT:AVISITVIS3
#> -0.04192625 -0.69368537
#> ARMCDTRT:AVISITVIS4
#> 0.62422703
#>
#> $beta_est_complete
#> (Intercept) RACEBlack or African American
#> 30.77747548 1.53049977
#> RACEWhite SEXFemale
#> 5.64356535 0.32606192
#> ARMCDTRT AVISITVIS2
#> 3.77423004 4.83958845
#> AVISITVIS3 AVISITVIS4
#> 10.34211288 15.05389826
#> ARMCDTRT:AVISITVIS2 ARMCDTRT:AVISITVIS3
#> -0.04192625 -0.69368537
#> ARMCDTRT:AVISITVIS4
#> 0.62422703
#>
#> $beta_aliased
#> (Intercept) RACEBlack or African American
#> FALSE FALSE
#> RACEWhite SEXFemale
#> FALSE FALSE
#> ARMCDTRT AVISITVIS2
#> FALSE FALSE
#> AVISITVIS3 AVISITVIS4
#> FALSE FALSE
#> ARMCDTRT:AVISITVIS2 ARMCDTRT:AVISITVIS3
#> FALSE FALSE
#> ARMCDTRT:AVISITVIS4
#> FALSE
#>
#> $x_matrix
#> (Intercept) RACEBlack or African American RACEWhite SEXFemale ARMCDTRT
#> 2 1 1 0 1 1
#> 4 1 1 0 1 1
#> 6 1 0 0 0 0
#> 7 1 0 0 0 0
#> 8 1 0 0 0 0
#> 10 1 1 0 1 0
#> 12 1 1 0 1 0
#> 13 1 0 0 1 1
#> 14 1 0 0 1 1
#> 16 1 0 0 1 1
#> 17 1 1 0 0 0
#> 19 1 1 0 0 0
#> 20 1 1 0 0 0
#> 23 1 1 0 0 0
#> 25 1 0 0 1 0
#> 26 1 0 0 1 0
#> 28 1 0 0 1 0
#> 29 1 1 0 0 0
#> 30 1 1 0 0 0
#> 31 1 1 0 0 0
#> 32 1 1 0 0 0
#> 33 1 0 1 0 1
#> 34 1 0 1 0 1
#> 36 1 0 1 0 1
#> 39 1 1 0 1 0
#> 41 1 0 0 1 1
#> 42 1 0 0 1 1
#> 43 1 0 0 1 1
#> 44 1 0 0 1 1
#> 45 1 0 0 0 0
#> 46 1 0 0 0 0
#> 47 1 0 0 0 0
#> 51 1 0 1 0 1
#> 52 1 0 1 0 1
#> 55 1 1 0 0 0
#> 59 1 0 0 0 0
#> 60 1 0 0 0 0
#> 62 1 0 0 1 0
#> 64 1 0 0 1 0
#> 65 1 0 1 1 0
#> 68 1 0 1 1 0
#> 69 1 0 0 0 1
#> 70 1 0 0 0 1
#> 72 1 0 0 0 1
#> 73 1 0 0 0 1
#> 74 1 0 0 0 1
#> 75 1 0 0 0 1
#> 76 1 0 0 0 1
#> 78 1 0 1 1 1
#> 79 1 0 1 1 1
#> 82 1 0 1 0 1
#> 83 1 0 1 0 1
#> 84 1 0 1 0 1
#> 85 1 0 1 0 1
#> 86 1 0 1 0 1
#> 87 1 0 1 0 1
#> 88 1 0 1 0 1
#> 89 1 1 0 1 0
#> 90 1 1 0 1 0
#> 91 1 1 0 1 0
#> 93 1 0 1 1 1
#> 94 1 0 1 1 1
#> 95 1 0 1 1 1
#> 96 1 0 1 1 1
#> 97 1 0 1 1 1
#> 98 1 0 1 1 1
#> 99 1 0 1 1 1
#> 100 1 0 1 1 1
#> 101 1 0 1 1 1
#> 102 1 0 1 1 1
#> 103 1 0 1 1 1
#> 104 1 0 1 1 1
#> 105 1 1 0 1 1
#> 107 1 1 0 1 1
#> 108 1 1 0 1 1
#> 109 1 1 0 0 1
#> 110 1 1 0 0 1
#> 111 1 1 0 0 1
#> 112 1 1 0 0 1
#> 113 1 1 0 0 1
#> 114 1 1 0 0 1
#> 116 1 1 0 0 1
#> 117 1 0 0 1 1
#> 118 1 0 0 1 1
#> 119 1 0 0 1 1
#> 120 1 0 0 1 1
#> 121 1 0 0 1 0
#> 123 1 0 0 1 0
#> 125 1 1 0 0 1
#> 128 1 1 0 0 1
#> 129 1 1 0 0 1
#> 130 1 1 0 0 1
#> 132 1 1 0 0 1
#> 133 1 0 0 1 0
#> 134 1 0 0 1 0
#> 135 1 0 0 1 0
#> 136 1 0 0 1 0
#> 137 1 1 0 1 1
#> 138 1 1 0 1 1
#> 140 1 1 0 1 1
#> 142 1 0 0 1 1
#> 144 1 0 0 1 1
#> 145 1 0 1 1 0
#> 146 1 0 1 1 0
#> 147 1 0 1 1 0
#> 148 1 0 1 1 0
#> 149 1 0 0 1 0
#> 151 1 0 0 1 0
#> 153 1 0 0 1 0
#> 155 1 0 0 1 0
#> 156 1 0 0 1 0
#> 157 1 1 0 0 0
#> 158 1 1 0 0 0
#> 159 1 1 0 0 0
#> 162 1 1 0 0 0
#> 163 1 1 0 0 0
#> 164 1 1 0 0 0
#> 165 1 1 0 0 0
#> 168 1 1 0 0 0
#> 169 1 1 0 1 1
#> 170 1 1 0 1 1
#> 171 1 1 0 1 1
#> 172 1 1 0 1 1
#> 173 1 1 0 0 1
#> 177 1 0 0 1 0
#> 178 1 0 0 1 0
#> 179 1 0 0 1 0
#> 180 1 0 0 1 0
#> 181 1 0 0 0 0
#> 182 1 0 0 0 0
#> 183 1 0 0 0 0
#> 185 1 0 0 0 1
#> 186 1 0 0 0 1
#> 187 1 0 0 0 1
#> 190 1 1 0 0 0
#> 191 1 1 0 0 0
#> 193 1 0 1 1 0
#> 194 1 0 1 1 0
#> 195 1 0 1 1 0
#> 197 1 0 0 1 1
#> 198 1 0 0 1 1
#> 199 1 0 0 1 1
#> 201 1 1 0 1 1
#> 202 1 1 0 1 1
#> 204 1 1 0 1 1
#> 206 1 1 0 1 1
#> 208 1 1 0 1 1
#> 209 1 0 1 0 0
#> 210 1 0 1 0 0
#> 217 1 0 0 0 1
#> 218 1 0 0 0 1
#> 219 1 0 0 0 1
#> 221 1 1 0 0 0
#> 224 1 1 0 0 0
#> 226 1 1 0 0 1
#> 227 1 1 0 0 1
#> 228 1 1 0 0 1
#> 230 1 0 1 1 1
#> 231 1 0 1 1 1
#> 233 1 0 1 1 1
#> 235 1 0 1 1 1
#> 236 1 0 1 1 1
#> 237 1 1 0 1 1
#> 238 1 1 0 1 1
#> 239 1 1 0 1 1
#> 240 1 1 0 1 1
#> 241 1 0 0 0 1
#> 242 1 0 0 0 1
#> 244 1 0 0 0 1
#> 246 1 0 0 1 0
#> 250 1 0 1 1 0
#> 251 1 0 1 1 0
#> 252 1 0 1 1 0
#> 253 1 1 0 1 0
#> 254 1 1 0 1 0
#> 256 1 1 0 1 0
#> 257 1 0 0 1 1
#> 258 1 0 0 1 1
#> 259 1 0 0 1 1
#> 260 1 0 0 1 1
#> 261 1 0 0 0 1
#> 262 1 0 0 0 1
#> 263 1 0 0 0 1
#> 264 1 0 0 0 1
#> 265 1 0 1 1 1
#> 266 1 0 1 1 1
#> 267 1 0 1 1 1
#> 268 1 0 1 1 1
#> 269 1 0 1 1 1
#> 270 1 0 1 1 1
#> 273 1 1 0 0 0
#> 274 1 1 0 0 0
#> 275 1 1 0 0 0
#> 276 1 1 0 0 0
#> 277 1 1 0 0 0
#> 278 1 1 0 0 0
#> 280 1 1 0 0 0
#> 281 1 0 0 0 1
#> 282 1 0 0 0 1
#> 283 1 0 0 0 1
#> 284 1 0 0 0 1
#> 285 1 0 0 1 1
#> 286 1 0 0 1 1
#> 287 1 0 0 1 1
#> 291 1 0 1 0 0
#> 292 1 0 1 0 0
#> 293 1 0 1 1 0
#> 295 1 0 1 1 0
#> 296 1 0 1 1 0
#> 298 1 0 1 0 0
#> 299 1 0 1 0 0
#> 300 1 0 1 0 0
#> 301 1 0 1 0 1
#> 304 1 0 1 0 1
#> 305 1 0 0 0 1
#> 306 1 0 0 0 1
#> 307 1 0 0 0 1
#> 308 1 0 0 0 1
#> 310 1 0 1 1 1
#> 311 1 0 1 1 1
#> 312 1 0 1 1 1
#> 316 1 0 0 1 0
#> 317 1 0 0 0 1
#> 318 1 0 0 0 1
#> 319 1 0 0 0 1
#> 322 1 0 1 0 0
#> 323 1 0 1 0 0
#> 324 1 0 1 0 0
#> 325 1 1 0 1 0
#> 327 1 1 0 1 0
#> 328 1 1 0 1 0
#> 329 1 0 1 0 1
#> 330 1 0 1 0 1
#> 331 1 0 1 0 1
#> 332 1 0 1 0 1
#> 336 1 0 0 1 0
#> 339 1 0 0 1 0
#> 340 1 0 0 1 0
#> 341 1 1 0 1 1
#> 342 1 1 0 1 1
#> 343 1 1 0 1 1
#> 344 1 1 0 1 1
#> 345 1 0 1 0 0
#> 347 1 0 1 0 0
#> 349 1 1 0 1 0
#> 351 1 1 0 1 0
#> 352 1 1 0 1 0
#> 353 1 1 0 0 0
#> 354 1 1 0 0 0
#> 355 1 1 0 0 0
#> 356 1 1 0 0 0
#> 357 1 0 0 0 0
#> 363 1 0 1 1 1
#> 364 1 0 1 1 1
#> 365 1 0 1 1 1
#> 367 1 0 1 1 1
#> 368 1 0 1 1 1
#> 370 1 1 0 0 0
#> 371 1 1 0 0 0
#> 372 1 1 0 0 0
#> 373 1 0 0 1 0
#> 375 1 0 0 1 0
#> 376 1 0 0 1 0
#> 378 1 0 0 1 0
#> 379 1 0 0 1 0
#> 381 1 1 0 1 0
#> 382 1 1 0 1 0
#> 384 1 1 0 1 0
#> 385 1 0 1 0 1
#> 386 1 0 1 0 1
#> 388 1 0 1 0 1
#> 389 1 0 0 0 0
#> 390 1 0 0 0 0
#> 391 1 0 0 0 0
#> 392 1 0 0 0 0
#> 394 1 1 0 0 0
#> 397 1 1 0 1 0
#> 398 1 1 0 1 0
#> 399 1 1 0 1 0
#> 402 1 0 1 0 1
#> 403 1 0 1 0 1
#> 405 1 0 0 1 0
#> 406 1 0 0 1 0
#> 407 1 0 0 1 0
#> 408 1 0 0 1 0
#> 409 1 0 0 1 0
#> 410 1 0 0 1 0
#> 411 1 0 0 1 0
#> 413 1 1 0 1 0
#> 415 1 1 0 1 0
#> 416 1 1 0 1 0
#> 418 1 1 0 1 1
#> 419 1 1 0 1 1
#> 421 1 0 0 1 1
#> 422 1 0 0 1 1
#> 423 1 0 0 1 1
#> 424 1 0 0 1 1
#> 427 1 0 1 1 0
#> 428 1 0 1 1 0
#> 429 1 0 1 0 1
#> 430 1 0 1 0 1
#> 431 1 0 1 0 1
#> 432 1 0 1 0 1
#> 434 1 1 0 1 0
#> 435 1 1 0 1 0
#> 436 1 1 0 1 0
#> 438 1 0 0 0 1
#> 439 1 0 0 0 1
#> 444 1 0 1 1 0
#> 445 1 1 0 1 0
#> 447 1 1 0 1 0
#> 449 1 0 0 0 0
#> 450 1 0 0 0 0
#> 451 1 0 0 0 0
#> 453 1 1 0 0 0
#> 454 1 1 0 0 0
#> 455 1 1 0 0 0
#> 456 1 1 0 0 0
#> 457 1 0 0 1 0
#> 458 1 0 0 1 0
#> 459 1 0 0 1 0
#> 461 1 1 0 0 1
#> 463 1 1 0 0 1
#> 464 1 1 0 0 1
#> 465 1 1 0 0 0
#> 469 1 0 0 1 0
#> 470 1 0 0 1 0
#> 471 1 0 0 1 0
#> 473 1 0 1 0 1
#> 474 1 0 1 0 1
#> 477 1 0 0 1 0
#> 484 1 1 0 0 1
#> 487 1 0 0 1 0
#> 489 1 0 1 1 0
#> 490 1 0 1 1 0
#> 491 1 0 1 1 0
#> 494 1 0 0 1 1
#> 495 1 0 0 1 1
#> 496 1 0 0 1 1
#> 497 1 0 1 0 0
#> 498 1 0 1 0 0
#> 499 1 0 1 0 0
#> 501 1 0 0 0 1
#> 502 1 0 0 0 1
#> 504 1 0 0 0 1
#> 505 1 1 0 1 1
#> 508 1 1 0 1 1
#> 509 1 0 0 1 1
#> 510 1 0 0 1 1
#> 511 1 0 0 1 1
#> 512 1 0 0 1 1
#> 513 1 0 1 0 1
#> 518 1 0 1 0 0
#> 519 1 0 1 0 0
#> 521 1 0 0 1 0
#> 522 1 0 0 1 0
#> 523 1 0 0 1 0
#> 524 1 0 0 1 0
#> 526 1 0 0 0 0
#> 527 1 0 0 0 0
#> 528 1 0 0 0 0
#> 530 1 0 1 0 0
#> 531 1 0 1 0 0
#> 532 1 0 1 0 0
#> 534 1 1 0 0 0
#> 535 1 1 0 0 0
#> 536 1 1 0 0 0
#> 537 1 1 0 0 0
#> 538 1 1 0 0 0
#> 539 1 1 0 0 0
#> 540 1 1 0 0 0
#> 541 1 0 1 1 1
#> 544 1 0 1 1 1
#> 545 1 0 0 1 1
#> 546 1 0 0 1 1
#> 547 1 0 0 1 1
#> 548 1 0 0 1 1
#> 549 1 0 0 0 1
#> 550 1 0 0 0 1
#> 551 1 0 0 0 1
#> 555 1 0 0 1 1
#> 556 1 0 0 1 1
#> 557 1 1 0 1 0
#> 558 1 1 0 1 0
#> 560 1 1 0 1 0
#> 562 1 0 1 0 1
#> 564 1 0 1 0 1
#> 569 1 1 0 1 1
#> 570 1 1 0 1 1
#> 572 1 1 0 1 1
#> 573 1 0 0 1 0
#> 574 1 0 0 1 0
#> 575 1 0 0 1 0
#> 576 1 0 0 1 0
#> 577 1 1 0 0 0
#> 578 1 1 0 0 0
#> 579 1 1 0 0 0
#> 582 1 0 0 1 1
#> 583 1 0 0 1 1
#> 584 1 0 0 1 1
#> 585 1 0 0 1 0
#> 586 1 0 0 1 0
#> 587 1 0 0 1 0
#> 590 1 1 0 0 1
#> 591 1 1 0 0 1
#> 593 1 0 0 1 0
#> 594 1 0 0 1 0
#> 595 1 0 0 1 0
#> 596 1 0 0 1 0
#> 599 1 0 1 0 0
#> 600 1 0 1 0 0
#> 601 1 0 0 1 0
#> 602 1 0 0 1 0
#> 604 1 0 0 1 0
#> 606 1 0 0 1 1
#> 608 1 0 0 1 1
#> 609 1 1 0 0 0
#> 610 1 1 0 0 0
#> 611 1 1 0 0 0
#> 612 1 1 0 0 0
#> 613 1 1 0 1 0
#> 614 1 1 0 1 0
#> 616 1 1 0 1 0
#> 617 1 0 0 0 1
#> 619 1 0 0 0 1
#> 620 1 0 0 0 1
#> 621 1 0 1 0 0
#> 622 1 0 1 0 0
#> 623 1 0 1 0 0
#> 624 1 0 1 0 0
#> 625 1 1 0 0 1
#> 628 1 1 0 0 1
#> 630 1 1 0 0 1
#> 631 1 1 0 0 1
#> 632 1 1 0 0 1
#> 633 1 0 0 1 1
#> 634 1 0 0 1 1
#> 638 1 0 0 0 1
#> 639 1 0 0 0 1
#> 640 1 0 0 0 1
#> 642 1 1 0 1 0
#> 645 1 0 0 0 0
#> 648 1 0 0 0 0
#> 650 1 0 1 0 0
#> 652 1 0 1 0 0
#> 654 1 1 0 1 0
#> 655 1 1 0 1 0
#> 656 1 1 0 1 0
#> 657 1 0 1 1 1
#> 661 1 0 0 0 1
#> 665 1 1 0 0 0
#> 666 1 1 0 0 0
#> 668 1 1 0 0 0
#> 669 1 1 0 1 0
#> 670 1 1 0 1 0
#> 671 1 1 0 1 0
#> 673 1 0 1 1 0
#> 674 1 0 1 1 0
#> 678 1 0 1 1 1
#> 679 1 0 1 1 1
#> 680 1 0 1 1 1
#> 682 1 0 0 1 0
#> 684 1 0 0 1 0
#> 685 1 0 0 1 1
#> 686 1 0 0 1 1
#> 687 1 0 0 1 1
#> 689 1 0 1 1 1
#> 690 1 0 1 1 1
#> 691 1 0 1 1 1
#> 693 1 1 0 1 1
#> 694 1 1 0 1 1
#> 695 1 1 0 1 1
#> 697 1 1 0 1 0
#> 698 1 1 0 1 0
#> 700 1 1 0 1 0
#> 701 1 1 0 0 1
#> 702 1 1 0 0 1
#> 704 1 1 0 0 1
#> 707 1 1 0 0 0
#> 709 1 1 0 0 0
#> 712 1 1 0 0 0
#> 713 1 0 1 0 1
#> 715 1 0 1 0 1
#> 716 1 0 1 0 1
#> 717 1 0 0 0 0
#> 718 1 0 0 0 0
#> 719 1 0 0 0 0
#> 721 1 0 0 1 0
#> 723 1 0 0 1 0
#> 724 1 0 0 1 0
#> 727 1 1 0 1 1
#> 728 1 1 0 1 1
#> 729 1 1 0 1 1
#> 730 1 1 0 1 1
#> 734 1 0 1 1 1
#> 736 1 0 1 1 1
#> 738 1 1 0 1 0
#> 739 1 1 0 1 0
#> 740 1 1 0 1 0
#> 741 1 0 1 0 0
#> 742 1 0 1 0 0
#> 744 1 0 1 0 0
#> 745 1 1 0 1 0
#> 749 1 1 0 1 0
#> 751 1 1 0 1 0
#> 753 1 0 0 1 1
#> 754 1 0 0 1 1
#> 755 1 0 0 1 1
#> 757 1 1 0 1 1
#> 758 1 1 0 1 1
#> 759 1 1 0 1 1
#> 760 1 1 0 1 1
#> 761 1 0 1 0 1
#> 764 1 0 1 0 1
#> 765 1 0 1 1 1
#> 766 1 0 1 1 1
#> 767 1 0 1 1 1
#> 768 1 0 1 1 1
#> 770 1 0 0 0 0
#> 771 1 0 0 0 0
#> 772 1 0 0 0 0
#> 773 1 1 0 0 0
#> 774 1 1 0 0 0
#> 775 1 1 0 0 0
#> 776 1 1 0 0 0
#> 778 1 0 1 1 1
#> 779 1 0 1 1 1
#> 781 1 0 0 0 0
#> 782 1 0 0 0 0
#> 784 1 0 0 0 0
#> 788 1 1 0 0 0
#> 789 1 1 0 0 1
#> 790 1 1 0 0 1
#> 792 1 1 0 0 1
#> 797 1 1 0 0 0
#> 798 1 1 0 0 0
#> 800 1 1 0 0 0
#> AVISITVIS2 AVISITVIS3 AVISITVIS4 ARMCDTRT:AVISITVIS2 ARMCDTRT:AVISITVIS3
#> 2 1 0 0 1 0
#> 4 0 0 1 0 0
#> 6 1 0 0 0 0
#> 7 0 1 0 0 0
#> 8 0 0 1 0 0
#> 10 1 0 0 0 0
#> 12 0 0 1 0 0
#> 13 0 0 0 0 0
#> 14 1 0 0 1 0
#> 16 0 0 1 0 0
#> 17 0 0 0 0 0
#> 19 0 1 0 0 0
#> 20 0 0 1 0 0
#> 23 0 1 0 0 0
#> 25 0 0 0 0 0
#> 26 1 0 0 0 0
#> 28 0 0 1 0 0
#> 29 0 0 0 0 0
#> 30 1 0 0 0 0
#> 31 0 1 0 0 0
#> 32 0 0 1 0 0
#> 33 0 0 0 0 0
#> 34 1 0 0 1 0
#> 36 0 0 1 0 0
#> 39 0 1 0 0 0
#> 41 0 0 0 0 0
#> 42 1 0 0 1 0
#> 43 0 1 0 0 1
#> 44 0 0 1 0 0
#> 45 0 0 0 0 0
#> 46 1 0 0 0 0
#> 47 0 1 0 0 0
#> 51 0 1 0 0 1
#> 52 0 0 1 0 0
#> 55 0 1 0 0 0
#> 59 0 1 0 0 0
#> 60 0 0 1 0 0
#> 62 1 0 0 0 0
#> 64 0 0 1 0 0
#> 65 0 0 0 0 0
#> 68 0 0 1 0 0
#> 69 0 0 0 0 0
#> 70 1 0 0 1 0
#> 72 0 0 1 0 0
#> 73 0 0 0 0 0
#> 74 1 0 0 1 0
#> 75 0 1 0 0 1
#> 76 0 0 1 0 0
#> 78 1 0 0 1 0
#> 79 0 1 0 0 1
#> 82 1 0 0 1 0
#> 83 0 1 0 0 1
#> 84 0 0 1 0 0
#> 85 0 0 0 0 0
#> 86 1 0 0 1 0
#> 87 0 1 0 0 1
#> 88 0 0 1 0 0
#> 89 0 0 0 0 0
#> 90 1 0 0 0 0
#> 91 0 1 0 0 0
#> 93 0 0 0 0 0
#> 94 1 0 0 1 0
#> 95 0 1 0 0 1
#> 96 0 0 1 0 0
#> 97 0 0 0 0 0
#> 98 1 0 0 1 0
#> 99 0 1 0 0 1
#> 100 0 0 1 0 0
#> 101 0 0 0 0 0
#> 102 1 0 0 1 0
#> 103 0 1 0 0 1
#> 104 0 0 1 0 0
#> 105 0 0 0 0 0
#> 107 0 1 0 0 1
#> 108 0 0 1 0 0
#> 109 0 0 0 0 0
#> 110 1 0 0 1 0
#> 111 0 1 0 0 1
#> 112 0 0 1 0 0
#> 113 0 0 0 0 0
#> 114 1 0 0 1 0
#> 116 0 0 1 0 0
#> 117 0 0 0 0 0
#> 118 1 0 0 1 0
#> 119 0 1 0 0 1
#> 120 0 0 1 0 0
#> 121 0 0 0 0 0
#> 123 0 1 0 0 0
#> 125 0 0 0 0 0
#> 128 0 0 1 0 0
#> 129 0 0 0 0 0
#> 130 1 0 0 1 0
#> 132 0 0 1 0 0
#> 133 0 0 0 0 0
#> 134 1 0 0 0 0
#> 135 0 1 0 0 0
#> 136 0 0 1 0 0
#> 137 0 0 0 0 0
#> 138 1 0 0 1 0
#> 140 0 0 1 0 0
#> 142 1 0 0 1 0
#> 144 0 0 1 0 0
#> 145 0 0 0 0 0
#> 146 1 0 0 0 0
#> 147 0 1 0 0 0
#> 148 0 0 1 0 0
#> 149 0 0 0 0 0
#> 151 0 1 0 0 0
#> 153 0 0 0 0 0
#> 155 0 1 0 0 0
#> 156 0 0 1 0 0
#> 157 0 0 0 0 0
#> 158 1 0 0 0 0
#> 159 0 1 0 0 0
#> 162 1 0 0 0 0
#> 163 0 1 0 0 0
#> 164 0 0 1 0 0
#> 165 0 0 0 0 0
#> 168 0 0 1 0 0
#> 169 0 0 0 0 0
#> 170 1 0 0 1 0
#> 171 0 1 0 0 1
#> 172 0 0 1 0 0
#> 173 0 0 0 0 0
#> 177 0 0 0 0 0
#> 178 1 0 0 0 0
#> 179 0 1 0 0 0
#> 180 0 0 1 0 0
#> 181 0 0 0 0 0
#> 182 1 0 0 0 0
#> 183 0 1 0 0 0
#> 185 0 0 0 0 0
#> 186 1 0 0 1 0
#> 187 0 1 0 0 1
#> 190 1 0 0 0 0
#> 191 0 1 0 0 0
#> 193 0 0 0 0 0
#> 194 1 0 0 0 0
#> 195 0 1 0 0 0
#> 197 0 0 0 0 0
#> 198 1 0 0 1 0
#> 199 0 1 0 0 1
#> 201 0 0 0 0 0
#> 202 1 0 0 1 0
#> 204 0 0 1 0 0
#> 206 1 0 0 1 0
#> 208 0 0 1 0 0
#> 209 0 0 0 0 0
#> 210 1 0 0 0 0
#> 217 0 0 0 0 0
#> 218 1 0 0 1 0
#> 219 0 1 0 0 1
#> 221 0 0 0 0 0
#> 224 0 0 1 0 0
#> 226 1 0 0 1 0
#> 227 0 1 0 0 1
#> 228 0 0 1 0 0
#> 230 1 0 0 1 0
#> 231 0 1 0 0 1
#> 233 0 0 0 0 0
#> 235 0 1 0 0 1
#> 236 0 0 1 0 0
#> 237 0 0 0 0 0
#> 238 1 0 0 1 0
#> 239 0 1 0 0 1
#> 240 0 0 1 0 0
#> 241 0 0 0 0 0
#> 242 1 0 0 1 0
#> 244 0 0 1 0 0
#> 246 1 0 0 0 0
#> 250 1 0 0 0 0
#> 251 0 1 0 0 0
#> 252 0 0 1 0 0
#> 253 0 0 0 0 0
#> 254 1 0 0 0 0
#> 256 0 0 1 0 0
#> 257 0 0 0 0 0
#> 258 1 0 0 1 0
#> 259 0 1 0 0 1
#> 260 0 0 1 0 0
#> 261 0 0 0 0 0
#> 262 1 0 0 1 0
#> 263 0 1 0 0 1
#> 264 0 0 1 0 0
#> 265 0 0 0 0 0
#> 266 1 0 0 1 0
#> 267 0 1 0 0 1
#> 268 0 0 1 0 0
#> 269 0 0 0 0 0
#> 270 1 0 0 1 0
#> 273 0 0 0 0 0
#> 274 1 0 0 0 0
#> 275 0 1 0 0 0
#> 276 0 0 1 0 0
#> 277 0 0 0 0 0
#> 278 1 0 0 0 0
#> 280 0 0 1 0 0
#> 281 0 0 0 0 0
#> 282 1 0 0 1 0
#> 283 0 1 0 0 1
#> 284 0 0 1 0 0
#> 285 0 0 0 0 0
#> 286 1 0 0 1 0
#> 287 0 1 0 0 1
#> 291 0 1 0 0 0
#> 292 0 0 1 0 0
#> 293 0 0 0 0 0
#> 295 0 1 0 0 0
#> 296 0 0 1 0 0
#> 298 1 0 0 0 0
#> 299 0 1 0 0 0
#> 300 0 0 1 0 0
#> 301 0 0 0 0 0
#> 304 0 0 1 0 0
#> 305 0 0 0 0 0
#> 306 1 0 0 1 0
#> 307 0 1 0 0 1
#> 308 0 0 1 0 0
#> 310 1 0 0 1 0
#> 311 0 1 0 0 1
#> 312 0 0 1 0 0
#> 316 0 0 1 0 0
#> 317 0 0 0 0 0
#> 318 1 0 0 1 0
#> 319 0 1 0 0 1
#> 322 1 0 0 0 0
#> 323 0 1 0 0 0
#> 324 0 0 1 0 0
#> 325 0 0 0 0 0
#> 327 0 1 0 0 0
#> 328 0 0 1 0 0
#> 329 0 0 0 0 0
#> 330 1 0 0 1 0
#> 331 0 1 0 0 1
#> 332 0 0 1 0 0
#> 336 0 0 1 0 0
#> 339 0 1 0 0 0
#> 340 0 0 1 0 0
#> 341 0 0 0 0 0
#> 342 1 0 0 1 0
#> 343 0 1 0 0 1
#> 344 0 0 1 0 0
#> 345 0 0 0 0 0
#> 347 0 1 0 0 0
#> 349 0 0 0 0 0
#> 351 0 1 0 0 0
#> 352 0 0 1 0 0
#> 353 0 0 0 0 0
#> 354 1 0 0 0 0
#> 355 0 1 0 0 0
#> 356 0 0 1 0 0
#> 357 0 0 0 0 0
#> 363 0 1 0 0 1
#> 364 0 0 1 0 0
#> 365 0 0 0 0 0
#> 367 0 1 0 0 1
#> 368 0 0 1 0 0
#> 370 1 0 0 0 0
#> 371 0 1 0 0 0
#> 372 0 0 1 0 0
#> 373 0 0 0 0 0
#> 375 0 1 0 0 0
#> 376 0 0 1 0 0
#> 378 1 0 0 0 0
#> 379 0 1 0 0 0
#> 381 0 0 0 0 0
#> 382 1 0 0 0 0
#> 384 0 0 1 0 0
#> 385 0 0 0 0 0
#> 386 1 0 0 1 0
#> 388 0 0 1 0 0
#> 389 0 0 0 0 0
#> 390 1 0 0 0 0
#> 391 0 1 0 0 0
#> 392 0 0 1 0 0
#> 394 1 0 0 0 0
#> 397 0 0 0 0 0
#> 398 1 0 0 0 0
#> 399 0 1 0 0 0
#> 402 1 0 0 1 0
#> 403 0 1 0 0 1
#> 405 0 0 0 0 0
#> 406 1 0 0 0 0
#> 407 0 1 0 0 0
#> 408 0 0 1 0 0
#> 409 0 0 0 0 0
#> 410 1 0 0 0 0
#> 411 0 1 0 0 0
#> 413 0 0 0 0 0
#> 415 0 1 0 0 0
#> 416 0 0 1 0 0
#> 418 1 0 0 1 0
#> 419 0 1 0 0 1
#> 421 0 0 0 0 0
#> 422 1 0 0 1 0
#> 423 0 1 0 0 1
#> 424 0 0 1 0 0
#> 427 0 1 0 0 0
#> 428 0 0 1 0 0
#> 429 0 0 0 0 0
#> 430 1 0 0 1 0
#> 431 0 1 0 0 1
#> 432 0 0 1 0 0
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#> 435 0 1 0 0 0
#> 436 0 0 1 0 0
#> 438 1 0 0 1 0
#> 439 0 1 0 0 1
#> 444 0 0 1 0 0
#> 445 0 0 0 0 0
#> 447 0 1 0 0 0
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#> 450 1 0 0 0 0
#> 451 0 1 0 0 0
#> 453 0 0 0 0 0
#> 454 1 0 0 0 0
#> 455 0 1 0 0 0
#> 456 0 0 1 0 0
#> 457 0 0 0 0 0
#> 458 1 0 0 0 0
#> 459 0 1 0 0 0
#> 461 0 0 0 0 0
#> 463 0 1 0 0 1
#> 464 0 0 1 0 0
#> 465 0 0 0 0 0
#> 469 0 0 0 0 0
#> 470 1 0 0 0 0
#> 471 0 1 0 0 0
#> 473 0 0 0 0 0
#> 474 1 0 0 1 0
#> 477 0 0 0 0 0
#> 484 0 0 1 0 0
#> 487 0 1 0 0 0
#> 489 0 0 0 0 0
#> 490 1 0 0 0 0
#> 491 0 1 0 0 0
#> 494 1 0 0 1 0
#> 495 0 1 0 0 1
#> 496 0 0 1 0 0
#> 497 0 0 0 0 0
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#> 499 0 1 0 0 0
#> 501 0 0 0 0 0
#> 502 1 0 0 1 0
#> 504 0 0 1 0 0
#> 505 0 0 0 0 0
#> 508 0 0 1 0 0
#> 509 0 0 0 0 0
#> 510 1 0 0 1 0
#> 511 0 1 0 0 1
#> 512 0 0 1 0 0
#> 513 0 0 0 0 0
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#> 519 0 1 0 0 0
#> 521 0 0 0 0 0
#> 522 1 0 0 0 0
#> 523 0 1 0 0 0
#> 524 0 0 1 0 0
#> 526 1 0 0 0 0
#> 527 0 1 0 0 0
#> 528 0 0 1 0 0
#> 530 1 0 0 0 0
#> 531 0 1 0 0 0
#> 532 0 0 1 0 0
#> 534 1 0 0 0 0
#> 535 0 1 0 0 0
#> 536 0 0 1 0 0
#> 537 0 0 0 0 0
#> 538 1 0 0 0 0
#> 539 0 1 0 0 0
#> 540 0 0 1 0 0
#> 541 0 0 0 0 0
#> 544 0 0 1 0 0
#> 545 0 0 0 0 0
#> 546 1 0 0 1 0
#> 547 0 1 0 0 1
#> 548 0 0 1 0 0
#> 549 0 0 0 0 0
#> 550 1 0 0 1 0
#> 551 0 1 0 0 1
#> 555 0 1 0 0 1
#> 556 0 0 1 0 0
#> 557 0 0 0 0 0
#> 558 1 0 0 0 0
#> 560 0 0 1 0 0
#> 562 1 0 0 1 0
#> 564 0 0 1 0 0
#> 569 0 0 0 0 0
#> 570 1 0 0 1 0
#> 572 0 0 1 0 0
#> 573 0 0 0 0 0
#> 574 1 0 0 0 0
#> 575 0 1 0 0 0
#> 576 0 0 1 0 0
#> 577 0 0 0 0 0
#> 578 1 0 0 0 0
#> 579 0 1 0 0 0
#> 582 1 0 0 1 0
#> 583 0 1 0 0 1
#> 584 0 0 1 0 0
#> 585 0 0 0 0 0
#> 586 1 0 0 0 0
#> 587 0 1 0 0 0
#> 590 1 0 0 1 0
#> 591 0 1 0 0 1
#> 593 0 0 0 0 0
#> 594 1 0 0 0 0
#> 595 0 1 0 0 0
#> 596 0 0 1 0 0
#> 599 0 1 0 0 0
#> 600 0 0 1 0 0
#> 601 0 0 0 0 0
#> 602 1 0 0 0 0
#> 604 0 0 1 0 0
#> 606 1 0 0 1 0
#> 608 0 0 1 0 0
#> 609 0 0 0 0 0
#> 610 1 0 0 0 0
#> 611 0 1 0 0 0
#> 612 0 0 1 0 0
#> 613 0 0 0 0 0
#> 614 1 0 0 0 0
#> 616 0 0 1 0 0
#> 617 0 0 0 0 0
#> 619 0 1 0 0 1
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#> 621 0 0 0 0 0
#> 622 1 0 0 0 0
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#> 625 0 0 0 0 0
#> 628 0 0 1 0 0
#> 630 1 0 0 1 0
#> 631 0 1 0 0 1
#> 632 0 0 1 0 0
#> 633 0 0 0 0 0
#> 634 1 0 0 1 0
#> 638 1 0 0 1 0
#> 639 0 1 0 0 1
#> 640 0 0 1 0 0
#> 642 1 0 0 0 0
#> 645 0 0 0 0 0
#> 648 0 0 1 0 0
#> 650 1 0 0 0 0
#> 652 0 0 1 0 0
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#> 656 0 0 1 0 0
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#> 661 0 0 0 0 0
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#> 668 0 0 1 0 0
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#> 673 0 0 0 0 0
#> 674 1 0 0 0 0
#> 678 1 0 0 1 0
#> 679 0 1 0 0 1
#> 680 0 0 1 0 0
#> 682 1 0 0 0 0
#> 684 0 0 1 0 0
#> 685 0 0 0 0 0
#> 686 1 0 0 1 0
#> 687 0 1 0 0 1
#> 689 0 0 0 0 0
#> 690 1 0 0 1 0
#> 691 0 1 0 0 1
#> 693 0 0 0 0 0
#> 694 1 0 0 1 0
#> 695 0 1 0 0 1
#> 697 0 0 0 0 0
#> 698 1 0 0 0 0
#> 700 0 0 1 0 0
#> 701 0 0 0 0 0
#> 702 1 0 0 1 0
#> 704 0 0 1 0 0
#> 707 0 1 0 0 0
#> 709 0 0 0 0 0
#> 712 0 0 1 0 0
#> 713 0 0 0 0 0
#> 715 0 1 0 0 1
#> 716 0 0 1 0 0
#> 717 0 0 0 0 0
#> 718 1 0 0 0 0
#> 719 0 1 0 0 0
#> 721 0 0 0 0 0
#> 723 0 1 0 0 0
#> 724 0 0 1 0 0
#> 727 0 1 0 0 1
#> 728 0 0 1 0 0
#> 729 0 0 0 0 0
#> 730 1 0 0 1 0
#> 734 1 0 0 1 0
#> 736 0 0 1 0 0
#> 738 1 0 0 0 0
#> 739 0 1 0 0 0
#> 740 0 0 1 0 0
#> 741 0 0 0 0 0
#> 742 1 0 0 0 0
#> 744 0 0 1 0 0
#> 745 0 0 0 0 0
#> 749 0 0 0 0 0
#> 751 0 1 0 0 0
#> 753 0 0 0 0 0
#> 754 1 0 0 1 0
#> 755 0 1 0 0 1
#> 757 0 0 0 0 0
#> 758 1 0 0 1 0
#> 759 0 1 0 0 1
#> 760 0 0 1 0 0
#> 761 0 0 0 0 0
#> 764 0 0 1 0 0
#> 765 0 0 0 0 0
#> 766 1 0 0 1 0
#> 767 0 1 0 0 1
#> 768 0 0 1 0 0
#> 770 1 0 0 0 0
#> 771 0 1 0 0 0
#> 772 0 0 1 0 0
#> 773 0 0 0 0 0
#> 774 1 0 0 0 0
#> 775 0 1 0 0 0
#> 776 0 0 1 0 0
#> 778 1 0 0 1 0
#> 779 0 1 0 0 1
#> 781 0 0 0 0 0
#> 782 1 0 0 0 0
#> 784 0 0 1 0 0
#> 788 0 0 1 0 0
#> 789 0 0 0 0 0
#> 790 1 0 0 1 0
#> 792 0 0 1 0 0
#> 797 0 0 0 0 0
#> 798 1 0 0 0 0
#> 800 0 0 1 0 0
#> ARMCDTRT:AVISITVIS4
#> 2 0
#> 4 1
#> 6 0
#> 7 0
#> 8 0
#> 10 0
#> 12 0
#> 13 0
#> 14 0
#> 16 1
#> 17 0
#> 19 0
#> 20 0
#> 23 0
#> 25 0
#> 26 0
#> 28 0
#> 29 0
#> 30 0
#> 31 0
#> 32 0
#> 33 0
#> 34 0
#> 36 1
#> 39 0
#> 41 0
#> 42 0
#> 43 0
#> 44 1
#> 45 0
#> 46 0
#> 47 0
#> 51 0
#> 52 1
#> 55 0
#> 59 0
#> 60 0
#> 62 0
#> 64 0
#> 65 0
#> 68 0
#> 69 0
#> 70 0
#> 72 1
#> 73 0
#> 74 0
#> 75 0
#> 76 1
#> 78 0
#> 79 0
#> 82 0
#> 83 0
#> 84 1
#> 85 0
#> 86 0
#> 87 0
#> 88 1
#> 89 0
#> 90 0
#> 91 0
#> 93 0
#> 94 0
#> 95 0
#> 96 1
#> 97 0
#> 98 0
#> 99 0
#> 100 1
#> 101 0
#> 102 0
#> 103 0
#> 104 1
#> 105 0
#> 107 0
#> 108 1
#> 109 0
#> 110 0
#> 111 0
#> 112 1
#> 113 0
#> 114 0
#> 116 1
#> 117 0
#> 118 0
#> 119 0
#> 120 1
#> 121 0
#> 123 0
#> 125 0
#> 128 1
#> 129 0
#> 130 0
#> 132 1
#> 133 0
#> 134 0
#> 135 0
#> 136 0
#> 137 0
#> 138 0
#> 140 1
#> 142 0
#> 144 1
#> 145 0
#> 146 0
#> 147 0
#> 148 0
#> 149 0
#> 151 0
#> 153 0
#> 155 0
#> 156 0
#> 157 0
#> 158 0
#> 159 0
#> 162 0
#> 163 0
#> 164 0
#> 165 0
#> 168 0
#> 169 0
#> 170 0
#> 171 0
#> 172 1
#> 173 0
#> 177 0
#> 178 0
#> 179 0
#> 180 0
#> 181 0
#> 182 0
#> 183 0
#> 185 0
#> 186 0
#> 187 0
#> 190 0
#> 191 0
#> 193 0
#> 194 0
#> 195 0
#> 197 0
#> 198 0
#> 199 0
#> 201 0
#> 202 0
#> 204 1
#> 206 0
#> 208 1
#> 209 0
#> 210 0
#> 217 0
#> 218 0
#> 219 0
#> 221 0
#> 224 0
#> 226 0
#> 227 0
#> 228 1
#> 230 0
#> 231 0
#> 233 0
#> 235 0
#> 236 1
#> 237 0
#> 238 0
#> 239 0
#> 240 1
#> 241 0
#> 242 0
#> 244 1
#> 246 0
#> 250 0
#> 251 0
#> 252 0
#> 253 0
#> 254 0
#> 256 0
#> 257 0
#> 258 0
#> 259 0
#> 260 1
#> 261 0
#> 262 0
#> 263 0
#> 264 1
#> 265 0
#> 266 0
#> 267 0
#> 268 1
#> 269 0
#> 270 0
#> 273 0
#> 274 0
#> 275 0
#> 276 0
#> 277 0
#> 278 0
#> 280 0
#> 281 0
#> 282 0
#> 283 0
#> 284 1
#> 285 0
#> 286 0
#> 287 0
#> 291 0
#> 292 0
#> 293 0
#> 295 0
#> 296 0
#> 298 0
#> 299 0
#> 300 0
#> 301 0
#> 304 1
#> 305 0
#> 306 0
#> 307 0
#> 308 1
#> 310 0
#> 311 0
#> 312 1
#> 316 0
#> 317 0
#> 318 0
#> 319 0
#> 322 0
#> 323 0
#> 324 0
#> 325 0
#> 327 0
#> 328 0
#> 329 0
#> 330 0
#> 331 0
#> 332 1
#> 336 0
#> 339 0
#> 340 0
#> 341 0
#> 342 0
#> 343 0
#> 344 1
#> 345 0
#> 347 0
#> 349 0
#> 351 0
#> 352 0
#> 353 0
#> 354 0
#> 355 0
#> 356 0
#> 357 0
#> 363 0
#> 364 1
#> 365 0
#> 367 0
#> 368 1
#> 370 0
#> 371 0
#> 372 0
#> 373 0
#> 375 0
#> 376 0
#> 378 0
#> 379 0
#> 381 0
#> 382 0
#> 384 0
#> 385 0
#> 386 0
#> 388 1
#> 389 0
#> 390 0
#> 391 0
#> 392 0
#> 394 0
#> 397 0
#> 398 0
#> 399 0
#> 402 0
#> 403 0
#> 405 0
#> 406 0
#> 407 0
#> 408 0
#> 409 0
#> 410 0
#> 411 0
#> 413 0
#> 415 0
#> 416 0
#> 418 0
#> 419 0
#> 421 0
#> 422 0
#> 423 0
#> 424 1
#> 427 0
#> 428 0
#> 429 0
#> 430 0
#> 431 0
#> 432 1
#> 434 0
#> 435 0
#> 436 0
#> 438 0
#> 439 0
#> 444 0
#> 445 0
#> 447 0
#> 449 0
#> 450 0
#> 451 0
#> 453 0
#> 454 0
#> 455 0
#> 456 0
#> 457 0
#> 458 0
#> 459 0
#> 461 0
#> 463 0
#> 464 1
#> 465 0
#> 469 0
#> 470 0
#> 471 0
#> 473 0
#> 474 0
#> 477 0
#> 484 1
#> 487 0
#> 489 0
#> 490 0
#> 491 0
#> 494 0
#> 495 0
#> 496 1
#> 497 0
#> 498 0
#> 499 0
#> 501 0
#> 502 0
#> 504 1
#> 505 0
#> 508 1
#> 509 0
#> 510 0
#> 511 0
#> 512 1
#> 513 0
#> 518 0
#> 519 0
#> 521 0
#> 522 0
#> 523 0
#> 524 0
#> 526 0
#> 527 0
#> 528 0
#> 530 0
#> 531 0
#> 532 0
#> 534 0
#> 535 0
#> 536 0
#> 537 0
#> 538 0
#> 539 0
#> 540 0
#> 541 0
#> 544 1
#> 545 0
#> 546 0
#> 547 0
#> 548 1
#> 549 0
#> 550 0
#> 551 0
#> 555 0
#> 556 1
#> 557 0
#> 558 0
#> 560 0
#> 562 0
#> 564 1
#> 569 0
#> 570 0
#> 572 1
#> 573 0
#> 574 0
#> 575 0
#> 576 0
#> 577 0
#> 578 0
#> 579 0
#> 582 0
#> 583 0
#> 584 1
#> 585 0
#> 586 0
#> 587 0
#> 590 0
#> 591 0
#> 593 0
#> 594 0
#> 595 0
#> 596 0
#> 599 0
#> 600 0
#> 601 0
#> 602 0
#> 604 0
#> 606 0
#> 608 1
#> 609 0
#> 610 0
#> 611 0
#> 612 0
#> 613 0
#> 614 0
#> 616 0
#> 617 0
#> 619 0
#> 620 1
#> 621 0
#> 622 0
#> 623 0
#> 624 0
#> 625 0
#> 628 1
#> 630 0
#> 631 0
#> 632 1
#> 633 0
#> 634 0
#> 638 0
#> 639 0
#> 640 1
#> 642 0
#> 645 0
#> 648 0
#> 650 0
#> 652 0
#> 654 0
#> 655 0
#> 656 0
#> 657 0
#> 661 0
#> 665 0
#> 666 0
#> 668 0
#> 669 0
#> 670 0
#> 671 0
#> 673 0
#> 674 0
#> 678 0
#> 679 0
#> 680 1
#> 682 0
#> 684 0
#> 685 0
#> 686 0
#> 687 0
#> 689 0
#> 690 0
#> 691 0
#> 693 0
#> 694 0
#> 695 0
#> 697 0
#> 698 0
#> 700 0
#> 701 0
#> 702 0
#> 704 1
#> 707 0
#> 709 0
#> 712 0
#> 713 0
#> 715 0
#> 716 1
#> 717 0
#> 718 0
#> 719 0
#> 721 0
#> 723 0
#> 724 0
#> 727 0
#> 728 1
#> 729 0
#> 730 0
#> 734 0
#> 736 1
#> 738 0
#> 739 0
#> 740 0
#> 741 0
#> 742 0
#> 744 0
#> 745 0
#> 749 0
#> 751 0
#> 753 0
#> 754 0
#> 755 0
#> 757 0
#> 758 0
#> 759 0
#> 760 1
#> 761 0
#> 764 1
#> 765 0
#> 766 0
#> 767 0
#> 768 1
#> 770 0
#> 771 0
#> 772 0
#> 773 0
#> 774 0
#> 775 0
#> 776 0
#> 778 0
#> 779 0
#> 781 0
#> 782 0
#> 784 0
#> 788 0
#> 789 0
#> 790 0
#> 792 1
#> 797 0
#> 798 0
#> 800 0
#> attr(,"assign")
#> [1] 0 1 1 2 3 4 4 4 5 5 5
#> attr(,"contrasts")
#> attr(,"contrasts")$RACE
#> [1] "contr.treatment"
#>
#> attr(,"contrasts")$SEX
#> [1] "contr.treatment"
#>
#> attr(,"contrasts")$ARMCD
#> [1] "contr.treatment"
#>
#> attr(,"contrasts")$AVISIT
#> [1] "contr.treatment"
#>
#>
#> $y_vector
#> [1] 39.97105 20.48379 31.45522 36.87889 48.80809 35.98699 37.16444 33.89229
#> [9] 33.74637 54.45055 32.31386 46.79361 41.71154 39.02423 31.93050 32.90947
#> [17] 48.28031 32.23021 35.91080 45.54898 53.02877 47.16898 46.64287 58.09713
#> [25] 44.97613 44.32755 38.97813 43.72862 46.43393 40.34576 42.76568 40.11155
#> [33] 53.31791 56.07641 41.90837 34.65663 39.07791 35.89612 47.67264 22.65440
#> [41] 40.85376 32.60048 33.64329 40.92278 32.14831 46.43604 41.34973 66.30382
#> [49] 47.95358 53.97364 56.64544 49.70872 60.40497 45.98525 51.90911 41.50787
#> [57] 53.42727 23.86859 35.98563 43.60626 29.59773 35.50688 55.42944 52.10530
#> [65] 31.69644 32.16159 51.04735 55.85987 49.11706 49.25544 51.72211 69.99128
#> [73] 22.07169 46.08393 52.42288 37.69466 44.59400 52.08897 58.22961 37.22824
#> [81] 34.39863 36.34012 45.44182 41.54847 43.92172 61.83243 27.25656 45.65133
#> [89] 33.19334 41.66826 27.12753 31.74858 41.60000 39.45250 32.61823 34.62445
#> [97] 45.90515 36.17780 39.79796 50.08272 44.64316 39.73529 34.06164 40.18592
#> [105] 41.17584 57.76669 38.18460 47.19893 37.32785 43.16048 41.40349 30.15733
#> [113] 35.84353 40.95250 41.37928 50.17316 45.35226 39.06491 42.11960 29.81042
#> [121] 42.57055 47.81652 68.06024 35.62071 33.89134 36.42808 37.57519 58.46873
#> [129] 19.54516 31.13541 40.89955 22.18809 41.05857 37.32452 43.12432 41.99349
#> [137] 44.03080 38.66417 53.45993 29.81948 30.43859 40.18095 26.78578 34.55115
#> [145] 40.06421 43.09329 45.71567 40.74992 44.74635 40.14674 48.75859 46.43462
#> [153] 29.33990 47.93165 41.11632 47.05889 52.24599 54.14236 50.44618 37.53657
#> [161] 49.45840 59.12866 40.31268 39.66049 50.89726 56.13116 32.82981 46.53837
#> [169] 51.81265 29.91939 51.05656 50.50059 64.11388 32.21843 29.64732 45.09919
#> [177] 39.75659 37.28894 44.80145 65.95920 33.43439 33.57042 39.91543 49.57098
#> [185] 38.91634 36.69011 45.66665 52.07431 42.21411 45.02901 30.98338 44.72932
#> [193] 40.68711 34.71530 27.30752 37.31585 44.83000 32.93042 44.91911 45.68636
#> [201] 65.98800 46.60130 40.89786 46.66708 43.83270 44.11604 38.29612 51.38570
#> [209] 56.20979 43.45819 38.38741 56.42818 39.05050 54.09200 31.40521 46.13330
#> [217] 45.29845 28.06936 42.50283 46.45368 64.97366 43.97847 35.33466 39.34378
#> [225] 41.27633 39.83058 43.49673 44.06114 41.43742 46.16954 54.24024 36.61831
#> [233] 42.09272 50.69556 51.72563 53.89947 39.94420 56.42482 41.86385 34.56420
#> [241] 38.68927 62.88743 28.85343 49.29495 28.74029 43.59994 57.38616 35.36824
#> [249] 43.06110 31.27551 54.13245 25.97050 51.17493 48.44043 43.33128 55.93546
#> [257] 54.15312 40.60252 44.44715 40.54161 33.95563 43.67802 42.76023 42.82678
#> [265] 39.59218 33.49216 35.39266 42.36266 48.54368 43.94366 47.91204 20.72928
#> [273] 28.00599 40.19255 37.79360 36.75177 34.59822 39.32034 40.65702 43.03255
#> [281] 54.65715 35.55742 43.70215 42.52157 54.89337 32.03460 29.45107 45.35138
#> [289] 38.73784 41.42283 47.32385 47.55310 49.06509 29.22591 40.08175 45.68142
#> [297] 41.47403 42.51970 69.36099 42.39760 43.72376 49.47601 51.94188 40.59100
#> [305] 39.97833 31.69049 37.20517 46.28740 41.58720 32.17365 40.69375 32.28771
#> [313] 41.76205 40.06768 29.14213 39.50989 43.32349 47.16756 40.93020 42.19406
#> [321] 41.21057 38.54330 43.96324 42.67652 22.79584 31.43559 38.85064 48.24288
#> [329] 44.71302 51.85370 30.56757 59.90473 49.76150 47.21985 40.34525 48.29793
#> [337] 44.39634 41.71421 47.37535 42.03797 37.56100 45.11793 34.62530 45.28206
#> [345] 63.57761 35.80878 52.67314 35.88734 38.73222 46.70361 53.65398 36.71543
#> [353] 41.54317 51.67909 27.40130 30.33517 37.73092 29.11668 32.08830 41.66067
#> [361] 53.90815 35.06937 47.17615 56.49347 38.88006 47.54070 43.53705 31.82054
#> [369] 39.62816 44.95543 21.11543 34.74671 56.69249 22.73126 32.50075 42.37206
#> [377] 42.89847 55.62582 45.38998 52.66743 34.18931 45.59740 28.89198 38.46147
#> [385] 49.90357 44.14167 55.24278 27.38001 33.63251 39.34410 26.98575 24.04175
#> [393] 42.16648 44.75380 31.55469 44.42696 44.10343 37.87445 48.31828 50.21520
#> [401] 41.94615 39.62690 46.69763 43.75255 47.38873 32.43412 43.07163 42.99551
#> [409] 53.82759 50.64802 63.44051 34.48949 40.08056 47.46553 37.11697 36.25120
#> [417] 29.20171 31.53773 42.35683 64.78352 32.72757 37.50022 57.03861 36.32475
#> [425] 41.46725 59.01411 30.14970 34.91740 52.13900 58.73839 35.83185 56.41409
#> [433] 43.55593 44.26320 59.25579 28.47314 47.47581 46.47483 51.22677 45.82777
#> [441] 39.06783 29.99542 54.17796 44.55743 62.59579 35.48396 44.07768 46.57837
#> [449] 47.67979 22.15439 34.27765 36.90059 40.54285 29.09494 37.21768 43.08491
#> [457] 27.12174 34.11916 40.80230 45.89269 43.69153 29.22869 55.68362 31.90698
#> [465] 37.31061 40.75546 42.19474 44.87228 47.55198 50.62894 45.47551 48.62168
#> [473] 29.66493 34.57406 38.11676 33.77204 34.26148 58.81037 39.88119 31.62708
#> [481] 48.22049 42.58829 49.33262 53.74331 29.71857 30.45651 38.29800 36.81040
#> [489] 42.35045 39.39860 49.73629 41.58082 43.58901 40.16762 41.08206 69.37409
#> [497] 41.27625 44.76138 39.69815 38.44296 48.20586 35.50735 32.08153 44.69256
#> [505] 42.18689 37.01741 38.26920 49.28806 40.45953 45.10337 45.58250 62.96989
#> [513] 30.78252 44.69667 32.72491 45.78702 48.74886 84.08449 30.19495 36.78573
#> [521] 61.03588 20.36749 35.22480 37.42847 30.20501 49.12862 47.31234 19.28388
#> [529] 30.00682 49.21768 40.13353 42.34534 52.32575 69.26254 35.70341 41.64454
#> [537] 54.25081
#>
#> $neg_log_lik
#> [1] 1693.225
#>
#> $jac_list
#> $jac_list[[1]]
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 1.16951547 -0.051411669 -4.500536e-02 -0.029651633 -1.11563537
#> [2,] -0.05141167 0.087578417 3.457645e-02 0.007196977 0.00260112
#> [3,] -0.04500536 0.034576445 8.503448e-02 0.007128258 -0.01178718
#> [4,] -0.02965163 0.007196977 7.128258e-03 0.061521074 -0.01065994
#> [5,] -1.11563537 0.002601120 -1.178718e-02 -0.010659937 2.28786967
#> [6,] -0.98171081 0.004118345 8.951822e-03 -0.003655354 0.97932241
#> [7,] -1.07753684 0.005790797 1.000235e-02 -0.006895078 1.07595394
#> [8,] -0.99821296 -0.001933166 8.676189e-03 -0.005754318 0.99903467
#> [9,] 0.97217159 0.008520375 1.325459e-02 0.002102199 -1.98758938
#> [10,] 1.06909044 0.008539116 5.337878e-03 0.004325848 -2.18658687
#> [11,] 0.99545698 0.001249297 7.858953e-05 0.008328731 -2.01758658
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] -0.981710811 -1.077536844 -0.998212960 0.972171586 1.069090436
#> [2,] 0.004118345 0.005790797 -0.001933166 0.008520375 0.008539116
#> [3,] 0.008951822 0.010002353 0.008676189 0.013254593 0.005337878
#> [4,] -0.003655354 -0.006895078 -0.005754318 0.002102199 0.004325848
#> [5,] 0.979322409 1.075953942 0.999034668 -1.987589379 -2.186586867
#> [6,] 0.836813950 0.933379638 0.857077689 -0.836557168 -0.933038454
#> [7,] 0.933379638 1.029968833 0.953510481 -0.932874939 -1.029216841
#> [8,] 0.857077689 0.953510481 0.877307817 -0.857056128 -0.953603898
#> [9,] -0.836557168 -0.932874939 -0.857056128 1.689099664 1.888995410
#> [10,] -0.933038454 -1.029216841 -0.953603898 1.888995410 2.089042080
#> [11,] -0.857161705 -0.953646838 -0.877357597 1.718938218 1.919022103
#> [,11]
#> [1,] 9.954570e-01
#> [2,] 1.249297e-03
#> [3,] 7.858953e-05
#> [4,] 8.328731e-03
#> [5,] -2.017587e+00
#> [6,] -8.571617e-01
#> [7,] -9.536468e-01
#> [8,] -8.773576e-01
#> [9,] 1.718938e+00
#> [10,] 1.919022e+00
#> [11,] 1.749781e+00
#>
#> $jac_list[[2]]
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 0.127530632 -0.129971302 -0.091071769 -0.098349416 -0.0096292734
#> [2,] -0.129971302 0.223312665 0.100844978 0.022808956 0.0192625869
#> [3,] -0.091071769 0.100844978 0.241127463 0.008554981 -0.0182023654
#> [4,] -0.098349416 0.022808956 0.008554981 0.158588894 0.0074601052
#> [5,] -0.009629273 0.019262587 -0.018202365 0.007460105 0.0052924416
#> [6,] 0.143539995 -0.001146971 -0.006231823 0.002417212 -0.1423316324
#> [7,] -0.005405883 0.005303578 -0.005757050 0.007567400 0.0017862785
#> [8,] -0.000946874 -0.001369925 -0.008947960 0.005898220 0.0012090250
#> [9,] -0.135790414 -0.003851407 -0.005449632 -0.008289146 0.2986740317
#> [10,] 0.009027932 0.004055441 -0.000926189 -0.019591078 0.0003322175
#> [11,] 0.010549853 -0.009420670 -0.001929567 -0.011019805 -0.0012298551
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] 0.143539995 -0.0054058831 -0.0009468740 -0.135790414 0.0090279324
#> [2,] -0.001146971 0.0053035778 -0.0013699251 -0.003851407 0.0040554408
#> [3,] -0.006231823 -0.0057570499 -0.0089479596 -0.005449632 -0.0009261890
#> [4,] 0.002417212 0.0075673998 0.0058982202 -0.008289146 -0.0195910780
#> [5,] -0.142331632 0.0017862785 0.0012090250 0.298674032 0.0003322175
#> [6,] 0.448003739 -0.1162181843 -0.0706352007 -0.448120908 0.1161018055
#> [7,] -0.116218184 0.0006208093 0.0004239335 0.115940070 -0.0006363704
#> [8,] -0.070635201 0.0004239335 0.0004185598 0.070507365 -0.0006302982
#> [9,] -0.448120908 0.1159400699 0.0705073651 0.858765561 -0.2400454620
#> [10,] 0.116101806 -0.0006363704 -0.0006302982 -0.240045462 0.0023653115
#> [11,] 0.070632347 -0.0007028855 -0.0003653049 -0.146687106 0.0008087299
#> [,11]
#> [1,] 0.0105498528
#> [2,] -0.0094206703
#> [3,] -0.0019295671
#> [4,] -0.0110198055
#> [5,] -0.0012298551
#> [6,] 0.0706323474
#> [7,] -0.0007028855
#> [8,] -0.0003653049
#> [9,] -0.1466871055
#> [10,] 0.0008087299
#> [11,] 0.0008254939
#>
#> $jac_list[[3]]
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 0.245560090 -0.241005288 -0.199099087 -0.186929231 -0.007083200
#> [2,] -0.241005288 0.415633400 0.207029802 0.031893969 0.028836257
#> [3,] -0.199099087 0.207029802 0.500748613 0.030611285 -0.048411146
#> [4,] -0.186929231 0.031893969 0.030611285 0.306670056 0.005230923
#> [5,] -0.007083200 0.028836257 -0.048411146 0.005230923 0.011939767
#> [6,] -0.006054804 0.001585372 -0.007248864 0.012399309 0.001516357
#> [7,] 0.038517951 0.007606844 -0.008011985 0.011376159 -0.044066774
#> [8,] -0.002604365 0.001058044 -0.013637333 0.008572980 0.002399258
#> [9,] 0.007160700 0.005781258 0.015632421 -0.023181005 -0.001960055
#> [10,] -0.036322394 0.009928403 0.006711191 -0.029277060 0.097958291
#> [11,] 0.012868838 -0.013894309 0.004513448 -0.013783909 -0.002935595
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] -0.0060548035 0.038517951 -0.0026043654 0.007160700 -0.036322394
#> [2,] 0.0015853720 0.007606844 0.0010580438 0.005781258 0.009928403
#> [3,] -0.0072488639 -0.008011985 -0.0136373325 0.015632421 0.006711191
#> [4,] 0.0123993093 0.011376159 0.0085729799 -0.023181005 -0.029277060
#> [5,] 0.0015163568 -0.044066774 0.0023992580 -0.001960055 0.097958291
#> [6,] 0.0005531211 -0.019244874 0.0005443283 -0.001131917 0.018650673
#> [7,] -0.0192448742 0.322767841 -0.0369215899 0.018771763 -0.322953100
#> [8,] 0.0005443283 -0.036921590 0.0006655005 -0.001070581 0.036691456
#> [9,] -0.0011319168 0.018771763 -0.0010705807 0.002312297 -0.037787975
#> [10,] 0.0186506733 -0.322953100 0.0366914555 -0.037787975 0.729050666
#> [11,] -0.0007378619 0.036578230 -0.0007538172 0.001139903 -0.078301890
#> [,11]
#> [1,] 0.0128688380
#> [2,] -0.0138943091
#> [3,] 0.0045134482
#> [4,] -0.0137839090
#> [5,] -0.0029355951
#> [6,] -0.0007378619
#> [7,] 0.0365782299
#> [8,] -0.0007538172
#> [9,] 0.0011399032
#> [10,] -0.0783018900
#> [11,] 0.0012934307
#>
#> $jac_list[[4]]
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 0.029388061 -0.0300363972 -0.0190464016 -0.0219001534 -0.0026139702
#> [2,] -0.030036397 0.0534144734 0.0204813833 0.0011759493 0.0060482951
#> [3,] -0.019046402 0.0204813833 0.0591610472 0.0004350294 -0.0075372943
#> [4,] -0.021900153 0.0011759493 0.0004350294 0.0391623541 0.0015980965
#> [5,] -0.002613970 0.0060482951 -0.0075372943 0.0015980965 0.0024815728
#> [6,] -0.001287289 0.0013882825 -0.0017696952 0.0017825394 0.0005500661
#> [7,] -0.001819822 0.0029497205 -0.0021392898 0.0014943281 0.0008816109
#> [8,] 0.120475742 0.0066564090 -0.0025523369 -0.0005390796 -0.1213358437
#> [9,] 0.001514454 0.0003149105 0.0035339826 -0.0042346457 -0.0006413058
#> [10,] 0.001998149 0.0003181908 0.0023183532 -0.0048503188 -0.0004152991
#> [11,] -0.121026181 -0.0031128838 0.0032728586 -0.0016022972 0.2665382625
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] -0.0012872891 -0.0018198218 0.1204757421 0.0015144537 0.0019981492
#> [2,] 0.0013882825 0.0029497205 0.0066564090 0.0003149105 0.0003181908
#> [3,] -0.0017696952 -0.0021392898 -0.0025523369 0.0035339826 0.0023183532
#> [4,] 0.0017825394 0.0014943281 -0.0005390796 -0.0042346457 -0.0048503188
#> [5,] 0.0005500661 0.0008816109 -0.1213358437 -0.0006413058 -0.0004152991
#> [6,] 0.0001286007 0.0001813006 -0.0503065912 -0.0002302344 -0.0001918272
#> [7,] 0.0001813006 0.0002904375 -0.1134126363 -0.0002434025 -0.0001634396
#> [8,] -0.0503065912 -0.1134126363 2.5685656978 0.0503712957 0.1139567512
#> [9,] -0.0002302344 -0.0002434025 0.0503712957 0.0005410878 0.0005376701
#> [10,] -0.0001918272 -0.0001634396 0.1139567512 0.0005376701 0.0005457575
#> [11,] 0.0502540492 0.1134358458 -2.5686970396 -0.1159679830 -0.2486909707
#> [,11]
#> [1,] -0.121026181
#> [2,] -0.003112884
#> [3,] 0.003272859
#> [4,] -0.001602297
#> [5,] 0.266538263
#> [6,] 0.050254049
#> [7,] 0.113435846
#> [8,] -2.568697040
#> [9,] -0.115967983
#> [10,] -0.248690971
#> [11,] 5.099408635
#>
#> $jac_list[[5]]
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 0.004551316 -0.0879251090 -0.0675549697 -0.0619695011 0.082243669
#> [2,] -0.087925109 0.1485375633 0.0683640555 0.0155723082 0.009620691
#> [3,] -0.067554970 0.0683640555 0.1594567207 0.0077525334 -0.017394272
#> [4,] -0.061969501 0.0155723082 0.0077525334 0.1048824324 -0.005511091
#> [5,] 0.082243669 0.0096206908 -0.0173942722 -0.0055110913 -0.156537882
#> [6,] 0.385905592 -0.0011341106 0.0027606978 -0.0059892150 -0.383415856
#> [7,] 0.077428636 0.0046614854 0.0022487032 0.0005457593 -0.079946648
#> [8,] 0.084542958 -0.0004665567 0.0005575602 -0.0003711182 -0.084356478
#> [9,] -0.386649427 -0.0035180888 -0.0074083952 0.0127403371 0.789358432
#> [10,] -0.082343916 0.0054837326 0.0048099471 -0.0025669755 0.163052708
#> [11,] -0.085004957 -0.0033454411 0.0014294624 0.0037285530 0.162124303
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] 0.385905592 0.0774286360 0.0845429585 -0.386649427 -0.082343916
#> [2,] -0.001134111 0.0046614854 -0.0004665567 -0.003518089 0.005483733
#> [3,] 0.002760698 0.0022487032 0.0005575602 -0.007408395 0.004809947
#> [4,] -0.005989215 0.0005457593 -0.0003711182 0.012740337 -0.002566976
#> [5,] -0.383415856 -0.0799466480 -0.0843564781 0.789358432 0.163052708
#> [6,] -0.453414690 -0.3488427144 -0.2936422304 0.453945775 0.349184039
#> [7,] -0.348842714 -0.0807840817 -0.0848246969 0.349077736 0.081076804
#> [8,] -0.293642230 -0.0848246969 -0.0924408766 0.293908832 0.084761720
#> [9,] 0.453945775 0.3490777360 0.2939088319 -0.944430402 -0.718327935
#> [10,] 0.349184039 0.0810768043 0.0847617199 -0.718327935 -0.165357544
#> [11,] 0.293825856 0.0847300392 0.0924354634 -0.593948987 -0.164508835
#> [,11]
#> [1,] -0.085004957
#> [2,] -0.003345441
#> [3,] 0.001429462
#> [4,] 0.003728553
#> [5,] 0.162124303
#> [6,] 0.293825856
#> [7,] 0.084730039
#> [8,] 0.092435463
#> [9,] -0.593948987
#> [10,] -0.164508835
#> [11,] -0.172559427
#>
#> $jac_list[[6]]
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 0.08542157 -0.137826561 -0.1282702232 -0.078379265 0.05003098
#> [2,] -0.13782656 0.220960935 0.1142518746 0.018491525 0.01153614
#> [3,] -0.12827022 0.114251875 0.2618437788 0.019186952 -0.02405239
#> [4,] -0.07837927 0.018491525 0.0191869519 0.160356324 -0.01893061
#> [5,] 0.05003098 0.011536139 -0.0240523934 -0.018930606 -0.06335921
#> [6,] 0.03659983 0.008950646 0.0157004609 -0.014175944 -0.03717414
#> [7,] 0.26882833 0.006132240 0.0150583035 -0.015518471 -0.26769477
#> [8,] 0.04288401 0.005444284 0.0157211567 -0.017201178 -0.04062223
#> [9,] -0.04557653 0.006113619 0.0075835994 0.007848601 0.06486011
#> [10,] -0.27641022 0.002373389 0.0003094496 0.014331910 0.54658686
#> [11,] -0.04574165 -0.002160889 -0.0032101287 0.015234861 0.06878771
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] 0.036599828 0.26882833 0.042884012 -0.045576528 -0.2764102205
#> [2,] 0.008950646 0.00613224 0.005444284 0.006113619 0.0023733885
#> [3,] 0.015700461 0.01505830 0.015721157 0.007583599 0.0003094496
#> [4,] -0.014175944 -0.01551847 -0.017201178 0.007848601 0.0143319097
#> [5,] -0.037174143 -0.26769477 -0.040622232 0.064860106 0.5465868612
#> [6,] -0.036537528 -0.18223535 -0.036883216 0.037420940 0.1835803939
#> [7,] -0.182235353 -0.43033005 -0.191856063 0.183200042 0.4313521431
#> [8,] -0.036883216 -0.19185606 -0.040133150 0.037660140 0.1929065668
#> [9,] 0.037420940 0.18320004 0.037660140 -0.066023556 -0.3692939735
#> [10,] 0.183580394 0.43135214 0.192906567 -0.369293973 -0.8905279201
#> [11,] 0.036772748 0.19190963 0.039985139 -0.065412140 -0.3881129679
#> [,11]
#> [1,] -0.045741653
#> [2,] -0.002160889
#> [3,] -0.003210129
#> [4,] 0.015234861
#> [5,] 0.068787712
#> [6,] 0.036772748
#> [7,] 0.191909629
#> [8,] 0.039985139
#> [9,] -0.065412140
#> [10,] -0.388112968
#> [11,] -0.069601485
#>
#> $jac_list[[7]]
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 0.114086163 -0.097427413 -0.083769143 -0.084335893 -0.015177889
#> [2,] -0.097427413 0.171565410 0.091327221 0.014994572 0.012589376
#> [3,] -0.083769143 0.091327221 0.214271278 0.021099078 -0.018328294
#> [4,] -0.084335893 0.014994572 0.021099078 0.128252724 0.003057876
#> [5,] -0.015177888 0.012589376 -0.018328294 0.003057876 0.026047595
#> [6,] -0.004551883 -0.009562540 -0.014683447 -0.005348839 0.015231549
#> [7,] -0.007876709 -0.005961614 -0.011655745 0.002717431 0.012237849
#> [8,] -0.010527492 -0.005408482 -0.012494865 0.007646903 0.012257406
#> [9,] 0.015278315 -0.001787167 -0.003423079 0.002034906 -0.026811770
#> [10,] 0.016026952 -0.001839693 0.001582606 -0.006787330 -0.021212851
#> [11,] 0.017090667 -0.004524006 0.001369913 -0.007745887 -0.022343966
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] -0.004551883 -0.007876709 -0.010527492 0.015278315 0.016026952
#> [2,] -0.009562540 -0.005961614 -0.005408482 -0.001787167 -0.001839693
#> [3,] -0.014683447 -0.011655745 -0.012494865 -0.003423079 0.001582606
#> [4,] -0.005348839 0.002717431 0.007646903 0.002034906 -0.006787330
#> [5,] 0.015231549 0.012237849 0.012257406 -0.026811770 -0.021212851
#> [6,] 0.004657885 0.186432595 0.014340663 -0.004729213 -0.186448877
#> [7,] 0.186432595 0.028282911 0.031912908 -0.186868010 -0.028980196
#> [8,] 0.014340663 0.031912908 0.011976141 -0.014607475 -0.032546095
#> [9,] -0.004729213 -0.186868010 -0.014607475 0.011985701 0.401133291
#> [10,] -0.186448877 -0.028980196 -0.032546095 0.401133291 0.054465595
#> [11,] -0.013914898 -0.031751346 -0.011780287 0.026473173 0.067484731
#> [,11]
#> [1,] 0.017090667
#> [2,] -0.004524006
#> [3,] 0.001369913
#> [4,] -0.007745887
#> [5,] -0.022343966
#> [6,] -0.013914898
#> [7,] -0.031751346
#> [8,] -0.011780287
#> [9,] 0.026473173
#> [10,] 0.067484731
#> [11,] 0.021879286
#>
#> $jac_list[[8]]
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] -0.00632345 -0.0330247357 -0.0306335895 -2.713874e-02 0.0429007253
#> [2,] -0.03302474 0.0689271627 0.0264214268 3.098127e-03 0.0007687068
#> [3,] -0.03063359 0.0264214268 0.0727011519 2.052435e-03 -0.0042893487
#> [4,] -0.02713874 0.0030981271 0.0020524349 5.004350e-02 -0.0033130642
#> [5,] 0.04290073 0.0007687068 -0.0042893487 -3.313064e-03 -0.0739170792
#> [6,] 0.03777660 -0.0029030180 0.0031236250 -8.298226e-05 -0.0379760333
#> [7,] 0.04017543 -0.0026049036 0.0036099233 -3.983313e-04 -0.0404707372
#> [8,] 0.59603872 0.0125429022 0.0064458743 -7.951492e-03 -0.5979172843
#> [9,] -0.03947397 0.0048333140 -0.0003088879 5.586368e-04 0.0703908762
#> [10,] -0.04173345 0.0069117346 -0.0021797914 -2.391208e-04 0.0750270552
#> [11,] -0.60670661 0.0066710186 0.0026709550 8.298984e-03 1.2937347687
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] 3.777660e-02 0.0401754343 0.596038719 -0.0394739661 -0.0417334546
#> [2,] -2.903018e-03 -0.0026049036 0.012542902 0.0048333140 0.0069117346
#> [3,] 3.123625e-03 0.0036099233 0.006445874 -0.0003088879 -0.0021797914
#> [4,] -8.298226e-05 -0.0003983313 -0.007951492 0.0005586368 -0.0002391208
#> [5,] -3.797603e-02 -0.0404707372 -0.597917284 0.0703908762 0.0750270552
#> [6,] -3.799992e-02 -0.0371638557 -0.388140283 0.0380613394 0.0369626471
#> [7,] -3.716386e-02 -0.0395400787 -0.528270623 0.0372504450 0.0393651521
#> [8,] -3.881403e-01 -0.5282706229 -0.719929656 0.3887917044 0.5296190355
#> [9,] 3.806134e-02 0.0372504450 0.388791704 -0.0710154532 -0.0696899327
#> [10,] 3.696265e-02 0.0393651521 0.529619035 -0.0696899327 -0.0737155799
#> [11,] 3.883582e-01 0.5289079321 0.719834718 -0.8523505466 -1.1452150099
#> [,11]
#> [1,] -0.606706606
#> [2,] 0.006671019
#> [3,] 0.002670955
#> [4,] 0.008298984
#> [5,] 1.293734769
#> [6,] 0.388358233
#> [7,] 0.528907932
#> [8,] 0.719834718
#> [9,] -0.852350547
#> [10,] -1.145215010
#> [11,] -1.607721763
#>
#> $jac_list[[9]]
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 0.041473959 -0.0314606272 -0.0168549200 -0.0231524166 -0.015155129
#> [2,] -0.031460627 0.0538809591 0.0221715386 0.0036557284 0.005427258
#> [3,] -0.016854920 0.0221715386 0.0558983069 -0.0009962606 -0.007335693
#> [4,] -0.023152417 0.0036557284 -0.0009962606 0.0381428652 0.004271950
#> [5,] -0.015155129 0.0054272576 -0.0073356932 0.0042719496 0.024739071
#> [6,] -0.014696964 0.0039311665 -0.0056690998 -0.0000112355 0.015484054
#> [7,] -0.013186168 0.0024647479 -0.0036293148 0.0026085423 0.012322919
#> [8,] -0.006261575 0.0137271545 -0.0049091072 -0.0033131287 0.005509253
#> [9,] 0.018453254 -0.0070166493 0.0002455207 -0.0023505381 -0.027859076
#> [10,] 0.014008277 0.0005465711 0.0030723292 -0.0065715204 -0.023077380
#> [11,] 0.004507731 -0.0020504017 0.0049401847 -0.0032191373 -0.020306631
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] -0.0146969636 -0.013186168 -0.006261574 0.0184532542 0.0140082769
#> [2,] 0.0039311665 0.002464748 0.013727155 -0.0070166493 0.0005465711
#> [3,] -0.0056690998 -0.003629315 -0.004909107 0.0002455207 0.0030723292
#> [4,] -0.0000112355 0.002608542 -0.003313129 -0.0023505381 -0.0065715204
#> [5,] 0.0154840543 0.012322919 0.005509253 -0.0278590763 -0.0230773802
#> [6,] 0.0039160699 0.014184770 0.435631004 -0.0039403699 -0.0138334893
#> [7,] 0.0141847700 0.011665630 0.022251231 -0.0143350648 -0.0116250116
#> [8,] 0.4356310036 0.022251231 0.108575190 -0.4352779840 -0.0209640018
#> [9,] -0.0039403698 -0.014335065 -0.435277984 0.0083177291 0.0267726469
#> [10,] -0.0138334891 -0.011625011 -0.020964002 0.0267726468 0.0233268432
#> [11,] -0.4357095614 -0.022010417 -0.108751449 0.9189699561 0.0633575579
#> [,11]
#> [1,] 0.004507731
#> [2,] -0.002050402
#> [3,] 0.004940185
#> [4,] -0.003219137
#> [5,] -0.020306631
#> [6,] -0.435709561
#> [7,] -0.022010417
#> [8,] -0.108751448
#> [9,] 0.918969956
#> [10,] 0.063357558
#> [11,] 0.246113616
#>
#> $jac_list[[10]]
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 0.047509505 -0.0400177876 -0.028260630 -0.034012888 -0.0080787362
#> [2,] -0.040017788 0.0684544433 0.031820681 0.003857395 0.0065759063
#> [3,] -0.028260630 0.0318206815 0.091939662 0.002503658 -0.0134695622
#> [4,] -0.034012887 0.0038573948 0.002503658 0.053295287 0.0039965501
#> [5,] -0.008078736 0.0065759063 -0.013469562 0.003996550 0.0125472203
#> [6,] -0.007063905 0.0004634755 -0.004672032 0.005868905 0.0054358762
#> [7,] -0.005445835 0.0014959340 -0.004698968 0.003207222 0.0049143606
#> [8,] -0.000808625 0.0032326140 0.008125468 -0.006370954 0.0003638005
#> [9,] 0.006892832 0.0013272345 0.007033864 -0.007504718 -0.0092578273
#> [10,] 0.006217393 -0.0029139736 0.005195181 -0.003467933 -0.0090043596
#> [11,] -0.011016188 0.0114643177 0.011169851 0.009527839 -0.0081867948
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] -0.0070639048 -0.005445835 -0.0008086251 0.006892832 0.006217394
#> [2,] 0.0004634755 0.001495934 0.0032326141 0.001327235 -0.002913974
#> [3,] -0.0046720325 -0.004698968 0.0081254684 0.007033864 0.005195181
#> [4,] 0.0058689047 0.003207222 -0.0063709544 -0.007504718 -0.003467933
#> [5,] 0.0054358762 0.004914360 0.0003638006 -0.009257828 -0.009004360
#> [6,] 0.0055361362 0.003344713 -0.0009680344 -0.005842300 -0.003635250
#> [7,] 0.0033447132 0.004126800 0.3172248299 -0.003525075 -0.004295166
#> [8,] -0.0009680343 0.317224830 -0.0604796213 0.001431163 -0.316729597
#> [9,] -0.0058423005 -0.003525075 0.0014311627 0.009950117 0.007200086
#> [10,] -0.0036352494 -0.004295166 -0.3167295969 0.007200085 0.009148940
#> [11,] 0.0008961252 -0.317074465 0.0602901477 0.008112531 0.703015371
#> [,11]
#> [1,] -0.0110161883
#> [2,] 0.0114643177
#> [3,] 0.0111698507
#> [4,] 0.0095278386
#> [5,] -0.0081867950
#> [6,] 0.0008961252
#> [7,] -0.3170744650
#> [8,] 0.0602901477
#> [9,] 0.0081125308
#> [10,] 0.7030153705
#> [11,] -0.1100765169
#>
#>
#> $theta_vcov
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 3.702524e-03 -1.215947e-04 -4.731168e-05 1.450739e-05 1.497878e-03
#> [2,] -1.215947e-04 4.166297e-03 5.181830e-06 -8.501705e-05 -2.892842e-03
#> [3,] -4.731168e-05 5.181830e-06 4.125814e-03 -1.641174e-05 -9.040069e-05
#> [4,] 1.450739e-05 -8.501705e-05 -1.641174e-05 3.954303e-03 1.872784e-04
#> [5,] 1.497878e-03 -2.892842e-03 -9.040069e-05 1.872784e-04 1.162924e-02
#> [6,] 9.528883e-04 -3.051437e-04 -1.464540e-03 1.037445e-04 1.171667e-03
#> [7,] -2.602792e-04 7.154405e-04 -1.610053e-04 -1.022748e-04 -8.342308e-04
#> [8,] 4.907597e-04 3.579757e-04 1.323707e-04 -1.731809e-03 -4.115907e-04
#> [9,] 2.835132e-05 1.522769e-04 -5.031469e-05 -5.113057e-06 -9.715561e-05
#> [10,] -7.267721e-05 -1.851224e-05 8.198068e-05 1.959919e-04 -1.454858e-04
#> [,6] [,7] [,8] [,9] [,10]
#> [1,] 0.0009528883 -0.0002602792 0.0004907597 2.835132e-05 -7.267721e-05
#> [2,] -0.0003051437 0.0007154405 0.0003579757 1.522769e-04 -1.851224e-05
#> [3,] -0.0014645400 -0.0001610053 0.0001323707 -5.031469e-05 8.198068e-05
#> [4,] 0.0001037445 -0.0001022748 -0.0017318089 -5.113057e-06 1.959919e-04
#> [5,] 0.0011716674 -0.0008342308 -0.0004115907 -9.715561e-05 -1.454858e-04
#> [6,] 0.0113483186 -0.0011633727 -0.0004920010 1.126993e-04 -1.244717e-04
#> [7,] -0.0011633727 0.0117530828 0.0003182121 -2.510208e-04 6.492154e-04
#> [8,] -0.0004920010 0.0003182121 0.0152793330 -2.440027e-03 1.085145e-03
#> [9,] 0.0001126993 -0.0002510208 -0.0024400268 9.713650e-03 -5.203255e-04
#> [10,] -0.0001244717 0.0006492154 0.0010851454 -5.203255e-04 1.123606e-02
#>
# Get convergence code and message.
component(fit, c("convergence", "conv_message"))
#> $convergence
#> [1] 0
#>
#> $conv_message
#> [1] "CONVERGENCE: REL_REDUCTION_OF_F <= FACTR*EPSMCH"
#>
# Get modeled formula as a string.
component(fit, c("formula"))
#> [1] "FEV1 ~ RACE + SEX + ARMCD * AVISIT + us(AVISIT | USUBJID)"