Calculates default bounds for non-linear parameters in dose-response models
defBnds.Rd
Calculates reasonable bounds for non-linear parameters for the built-in non-linear regression model based on the dose range under investigation.
For the logistic model the first row corresponds to the ED50 parameter and the
second row to the delta parameter. For the sigmoid Emax model the
first row corresponds to the ED50 parameter and the second row to the
h parameter, while for the beta model first and second row correspond
to the delta1 and delta2 parameters. See logistic
,
sigEmax
and betaMod
for details.
Examples
defBnds(mD = 1)
#> $emax
#> [1] 0.001 1.500
#>
#> $logistic
#> [,1] [,2]
#> [1,] 0.001 1.5
#> [2,] 0.010 0.5
#>
#> $sigEmax
#> [,1] [,2]
#> [1,] 0.001 1.5
#> [2,] 0.500 10.0
#>
#> $exponential
#> [1] 0.1 2.0
#>
#> $betaMod
#> [,1] [,2]
#> [1,] 0.05 4
#> [2,] 0.05 4
#>
defBnds(mD = 200)
#> $emax
#> [1] 0.2 300.0
#>
#> $logistic
#> [,1] [,2]
#> [1,] 0.2 300
#> [2,] 2.0 100
#>
#> $sigEmax
#> [,1] [,2]
#> [1,] 0.2 300
#> [2,] 0.5 10
#>
#> $exponential
#> [1] 20 400
#>
#> $betaMod
#> [,1] [,2]
#> [1,] 0.05 4
#> [2,] 0.05 4
#>