Get Eligible Doses from the Dose Grid.

Helper function that gets the eligible doses from the dose grid. The eligible doses are the doses which do not exceed a given doselimit. For placebo design, if safety allows (i.e. if there is at least one non-placebo dose which does not exceed the dose limit), the placebo dose it then excluded from the eligible doses.

Usage

h_next_best_eligible_doses(dose_grid, doselimit, placebo, levels = FALSE)

Arguments

dose_grid

(numeric)
all possible doses.

doselimit

(number)
the maximum allowed next dose.

placebo

(flag)
if TRUE the first dose level in the dose_grid is considered as placebo.

levels

(flag)
if TRUE the levels of eligible doses are returned, otherwise, the doses (default).

Value

A numeric vector with eligible doses or eligible dose levels if levels flag is TRUE.

Examples

dose_grid <- c(0.001, seq(25, 200, 25))
h_next_best_eligible_doses(dose_grid, 79, TRUE)
#> [1] 25 50 75
h_next_best_eligible_doses(dose_grid, 24, TRUE)
#> [1] 0.001