NextBestInfTheory

NextBestInfTheory is the class for next best dose that is based on information theory as proposed in https://doi.org/10.1002/sim.8450.

Usage

NextBestInfTheory(target, asymmetry)

.DefaultNextBestInfTheory()

Arguments

target

(proportion)
see slot definition.

asymmetry

(number)
see slot definition.

Slots

target

(proportion)
target toxicity probability, except 0 or 1.

asymmetry

(number)
value of the asymmetry exponent in the divergence function that describes the rate of penalization for overly toxic does. It must be a value from \((0, 2)\) interval.

Note

Typically, end users will not use the .DefaultNextBestInfTheory() function.