Helper function to determine the dlts including first separate and placebo condition
Source:R/helpers_design.R
h_determine_dlts.RdHelper function to determine the dlts including first separate and placebo condition
Usage
h_determine_dlts(
data,
dose,
prob,
prob_placebo,
cohort_size,
cohort_size_placebo,
dose_grid,
first_separate
)Arguments
- data
(
Data)
what data to start from.- dose
(
number)
current dose.- prob
(
function)
defines the true probability for a DLT at a dose.- prob_placebo
(
function)
defines the true probability for a DLT at a placebo condition.- cohort_size
(
number)
the cohort size to use.- cohort_size_placebo
(
number)
the cohort size to use for placebo condition.- dose_grid
(
numeric)
the dose_grid as specified by the user.- first_separate
(
flag)
whether the first patient is enrolled separately.