This function combines cohort size rules by taking the maximum of all sizes.
Arguments
- ...
Objects of class
CohortSize
Value
the combination as an object of class
CohortSizeMax
Examples
# Here is the rule for:
# having cohort of size 1 for doses <30
# and having cohort of size 3 for doses >=30
mySize1 <- CohortSizeRange(intervals = c(0, 30), cohort_size = c(1, 3))
# Here is the rule for:
# having cohort of size 1 until no DLT were observed
# and having cohort of size 3 as soon as 1 DLT is observed
mySize2 <- CohortSizeDLT(intervals = c(0, 1), cohort_size = c(1, 3))
# This is combining the two rules above by taking the maximum of the sample sizes of
# the single rules
mySize <- maxSize(mySize1, mySize2)