Plot patient visits against visit_med75. — plot_visit

Plots cumulative AEs against visits for patients at sites of given study and compares against visit_med75.

Usage

plot_visit_med75(
  df_visit,
  df_site = NULL,
  study_id_str,
  n_sites = 6,
  min_pat_pool = 0.2,
  verbose = TRUE,
  event_names = "ae",
  plot_event = "ae",
  ...
)

Arguments

df_visit: dataframe
df_site: dataframe, as returned by site_aggr()
study_id_str: character, specify study in study_id column
n_sites: integer, Default: 6
min_pat_pool: double, minimum ratio of available patients available for sampling. Determines maximum visit_med75 value see Details. Default: 0.2
verbose: logical, Default: TRUE
event_names: vector, contains the event names, default = "ae"
plot_event: vector containing the events that should be plotted, default = "ae"
...: not used

Value

ggplot

Examples

df_visit <- sim_test_data_study(
  n_pat = 120,
  n_sites = 6,
  ratio_out = 0.4,
  factor_event_rate = - 0.6
 ) %>%
 dplyr::rename(
  site_number = site_id,
  patnum = patient_id,
  n_ae = n_event
 )

df_site <- site_aggr(df_visit)

simaerep:::plot_visit_med75(df_visit, df_site, study_id_str = "A", n_site = 6)
#> purple line:          mean site ae of patients with visit_med75
#> grey line:            patient included
#> black dashed line:    patient excluded
#> dotted vertical line: visit_med75, 0.75 x median of maximum patient visits of site 
#> solid vertical line:  visit_med75 adjusted, increased to minimum maximum patient visit of included patients
#> dashed vertical line: maximum value for visit_med75 adjusted, 80% quantile of maximum patient visits of study
#>