ModelTox
is the parent class for DLE (dose-limiting events) models using
pseudo data prior. It is dedicated for DLE models or toxicity models that
have their prior specified in the form of pseudo data (as if there is some
data before the trial starts).
The data
must obey the convention of the Data
class. This refers to any
observed DLE responses (y
in Data
), the dose levels (x
in Data
)
at which these responses are observed, all dose levels considered in the
study (doseGrid
in Data
), and finally other specifications in Data
class that can be used to generate prior or posterior modal estimates or
samples estimates for model parameter(s).
If no responses are observed, at least doseGrid
has to be specified
in data
for which prior modal estimates or samples can be obtained for
model parameters based on the specified pseudo data.
Slots
data
(
Data
)
observed data that is used to obtain model parameters estimates or samples (see details above).